Ameloblastin Antibody (H-2): sc-271012
- Ameloblastin Antibody (H-2) is a mouse monoclonal IgG1 κ Ameloblastin antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 148-447 mapping at the C-terminus of Ameloblastin of human origin
- Ameloblastin Antibody (H-2) is recommended for detection of Ameloblastin of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Ameloblastin Antibody (H-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Ameloblastin (H-2): sc-271012.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Ameloblastin Antibody (H-2) for WB and IHC(P) applications. These reagents are now offered in bundles with Ameloblastin Antibody (H-2) (see ordering information below).
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SEE ALSO...
Ameloblastin Antibody (H-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ameloblastin of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Ameloblastin antibody (H-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Ameloblastin plays a crucial role in dental enamel development, a highly mineralized tissue primarily composed of hydroxyapatite crystals. Ameloblastin (H-2) antibody specifically detects this protein in the extracellular matrix, where Ameloblastin is essential for proper formation and mineralization of the enamel matrix during tooth development. Ameloblastin interacts with other key proteins such as amelogenin and enamelin, contributing to the structural integrity and organization of enamel. Defects in the AMBN gene, which encodes for Ameloblastin, have been associated with conditions like ameloblastomas, highlighting Ameloblastin′s significance in dental health. Anti-Ameloblastin antibody (H-2)′s ability to effectively detect Ameloblastin across various applications makes this reagent an invaluable tool for researchers studying enamel formation and related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ameloblastin Antibody (H-2) References:
- Cloning, characterization and immunolocalization of human ameloblastin. | MacDougall, M., et al. 2000. Eur J Oral Sci. 108: 303-10. PMID: 10946765
- Cloning and characterization of the human ameloblastin gene. | Toyosawa, S., et al. 2000. Gene. 256: 1-11. PMID: 11054529
- Human ameloblastin gene: genomic organization and mutation analysis in amelogenesis imperfecta patients. | Mårdh, CK., et al. 2001. Eur J Oral Sci. 109: 8-13. PMID: 11330937
- Ameloblastin and amelogenin expression in posnatal developing mouse molars. | Torres-Quintana, MA., et al. 2005. J Oral Sci. 47: 27-34. PMID: 15881226
- Enamel matrix protein interactions. | Wang, H., et al. 2005. J Bone Miner Res. 20: 1032-40. PMID: 15883644
- Expression of ameloblastin during enamel formation in a crocodile. | Shintani, S., et al. 2006. J Exp Zool B Mol Dev Evol. 306: 126-33. PMID: 16217799
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ameloblastin Antibody (H-2) | sc-271012 | 200 µg/ml | $316.00 | |||
Ameloblastin Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-527202 | 200 µg Ab; 10 µg BP | $354.00 | |||
Ameloblastin Antibody (H-2): m-IgG1 BP-HRP Bundle | sc-532575 | 200 µg Ab; 20 µg BP | $354.00 | |||
Ameloblastin Antibody (H-2) AC | sc-271012 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Ameloblastin Antibody (H-2) HRP | sc-271012 HRP | 200 µg/ml | $316.00 | |||
Ameloblastin Antibody (H-2) FITC | sc-271012 FITC | 200 µg/ml | $330.00 | |||
Ameloblastin Antibody (H-2) PE | sc-271012 PE | 200 µg/ml | $343.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 488 | sc-271012 AF488 | 200 µg/ml | $357.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 546 | sc-271012 AF546 | 200 µg/ml | $357.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 594 | sc-271012 AF594 | 200 µg/ml | $357.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 647 | sc-271012 AF647 | 200 µg/ml | $357.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 680 | sc-271012 AF680 | 200 µg/ml | $357.00 | |||
Ameloblastin Antibody (H-2) Alexa Fluor® 790 | sc-271012 AF790 | 200 µg/ml | $357.00 |