ALX1 Antibody (3329D3a): sc-130642
- ALX1 Antibody (3329D3a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the N-terminus of ALX1 of human origin
- recommended for detection of ALX1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ALX1 Antibody (3329D3a). This work is in progress.
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ALX1 Antibody (3329D3a) is a mouse monoclonal IgG1 antibody that detects ALX1 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). ALX1, also known as CART-1, is a 326 amino acid protein primarily expressed in cervix and cartilage tissues, playing a crucial role in regulating cell development and pattern formation during embryonic stages. ALX1 features a homeobox domain, which is essential for its function as a transcription factor, and an OAR domain that facilitates DNA binding and protein-protein interactions, thereby influencing transactivation processes. ALX1′s significance is underscored by its involvement in the regulation of downstream target genes, including its role as a transcriptional repressor for rat prolactin in vivo. Studies have shown that homozygous ALX1 deficient mice exhibit severe developmental defects such as acrania and meroanencephaly, highlighting ALX1′s critical function in neural tube development. Furthermore, ALX1 has been implicated in limb development and craniofacial bone formation through cooperation with ALX4, making ALX1 a vital component in the intricate processes of embryonic development. With specific reactivity to human tissues and proven applications, anti-ALX1 antibody (3329D3a) serves as an invaluable tool for researchers studying developmental biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALX1 Antibody (3329D3a) | sc-130642 | 100 µg/ml | $333.00 |