alpha Tubulin Antibody (AA13): sc-58668

α Tubulin Antibody (AA13) is a mouse monoclonal IgG2a antibody that specifically recognizes α Tubulin, a key protein of the cytoskeleton, in mouse, rat, and human tissues. anti-α Tubulin antibody (AA13) is raised against brain-derived tubulin from rat origin and is suitable for use in various applications, including western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). α Tubulin is a critical structural component of microtubules, where α Tubulin forms heterodimers with β Tubulin to generate microtubule filaments that play essential roles in intracellular transport, mitosis, and cell shape maintenance. Microtubules are dynamic structures that interact with various motor proteins, including dynein and kinesin, which use microtubules as tracks for the movement of organelles, vesicles, and protein complexes. Additionally, α Tubulin interacts with microtubule-associated proteins (MAPs) such as tau and MAP2, which stabilize microtubules and regulate microtubule assembly and disassembly. α Tubulin is also involved in processes like ciliary and flagellar movement, where α Tubulin forms the structural basis for axonemal microtubules. Post-translational modifications of α Tubulin, such as acetylation, detyrosination, and phosphorylation, are crucial for regulating microtubule stability and interactions with motor proteins and MAPs. These modifications help control microtubule dynamics, which are vital for functions such as cell division, cell signaling, and the maintenance of cellular organization. α Tubulin monoclonal antibody (AA13) is a useful tool for studying these interactions and modifications, providing valuable insights into the regulation of microtubule dynamics and their role in cellular processes.

The preferred alpha Tubulin antibody is alpha Tubulin Antibody (TU-02): sc-8035.