alpha Tubulin Antibody (AA12): sc-58667

α Tubulin Antibody (AA12) is a mouse monoclonal IgG2a antibody designed to detect α Tubulin, a core component of the cytoskeleton, in mouse, rat, and human samples. Anti-α Tubulin antibody (AA12) is raised against synthetic α Tubulin derived from human sources and is suitable for use in western blotting (WB) and immunoprecipitation (IP) applications. α Tubulin, a highly conserved protein, is one of the two subunits of microtubules, forming heterodimers with β Tubulin to create the structural framework of microtubules. These microtubules are essential for maintaining cell shape, facilitating intracellular transport, and supporting cell division by organizing the mitotic spindle during mitosis. Additionally, α Tubulin plays a crucial role in the formation of cilia and flagella, structures responsible for motility and sensory functions. α Tubulin exists in various isoforms and undergoes post-translational modifications, such as tyrosination and detyrosination, which regulate its dynamics and interactions with motor proteins like kinesin and dynein. These modifications are vital for controlling microtubule stability and function, particularly in processes such as cell signaling, mitosis, and organelle movement. α Tubulin monoclonal antibody (AA12) is invaluable for studying microtubule dynamics and understanding the role of post-translational modifications in regulating cellular architecture and function.

The preferred alpha Tubulin antibody is alpha Tubulin Antibody (TU-02): sc-8035.