Date published: 2025-10-8

1-800-457-3801

SCBT Portrait Logo
Seach Input

ALK Antibody (ALK1): sc-53157

4.3(3)
Write a reviewAsk a question

Datasheets
  • ALK Antibody (ALK1) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
  • raised against amino acids 419-520 of ALK of human origin
  • recommended for detection of ALK of human origin by WB, IP, IF and FCM
  • See ALK (F-12): sc-398791 for ALK antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG3 BP-HRP is the preferred secondary detection reagent for ALK Antibody (ALK1) for WB applications. This reagent is now offered in a bundle with ALK Antibody (ALK1) (see ordering information below).

    QUICK LINKS

    SEE ALSO...

    ALK Antibody (ALK1) is a mouse monoclonal IgG3 antibody engineered to target the anaplastic lymphoma kinase (ALK) protein, also known as NPM-ALK in certain oncogenic contexts. ALK is a receptor tyrosine kinase that plays a pivotal role in the development and maintenance of the nervous system by regulating neuronal growth, differentiation, and survival. ALK protein is crucial for normal physiological processes, and dysregulation is associated with various cancers, including anaplastic large cell lymphoma, non-small cell lung cancer, and neuroblastoma, making ALK a vital target for cancer research and therapeutic interventions. Anti-ALK antibody (ALK1) is raised against amino acids 419-520 of human ALK protein. ALK monoclonal antibody (ALK1) demonstrates robust reactivity with human ALK in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM), making ALK (ALK1) antibody a versatile research tool. By facilitating precise detection and analysis of ALK expression and activity, ALK (ALK1) monoclonal antibody enables investigation of ALK-related signaling pathways and development of targeted therapies. With comprehensive functionality, anti-ALK antibody (ALK1) supports advancements in studying ALK′s role in oncogenesis and normal cellular processes, contributing to development of effective diagnostic and therapeutic strategies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    ALK Antibody (ALK1)

    sc-53157
    200 µg/ml
    $316.00

    ALK Antibody (ALK1): m-IgG3 BP-HRP Bundle

    sc-550373
    200 µg Ab; 40 µg BP
    $354.00

    What is the recommended starting dilution for Western blot for sc-53157: ALK (ALK1) monoclonal antibody?

    Asked by: cjMara
    The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-22
    • y_2025, m_9, d_24, h_6CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_en_US, sid_53157, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 113ms
    • QUESTIONS, PRODUCT
    Rated 4 out of 5 by from 该抗体抗原相关问题https://ashpublications.org/blood/article/89/4/1394/139101/Detection-of-Anaplastic-Lymphoma-Kinase-ALK-and 从文献来看 ALK1抗体的抗原419-520aa其实位于NPM1-ALK的C端?
    Date published: 2024-11-18
    Rated 5 out of 5 by from Works well for wbIt worked well when I used this antibody for western blot of recombinant human ALK protein.
    Date published: 2016-11-22
    • y_2025, m_9, d_24, h_6
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_1, tr_2
    • loc_en_US, sid_53157, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 18ms
    • REVIEWS, PRODUCT
    ALK Antibody (ALK1) is rated 4.3 out of 5 by 3.
    • y_2025, m_9, d_24, h_6
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_1, tr_2
    • loc_en_US, sid_53157, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 107ms
    • REVIEWS, PRODUCT