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Alix Antibody (2H12) is a mouse monoclonal IgG1 antibody that detects Alix in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Alix, also known as programmed cell death 6-interacting protein, plays a crucial role in cellular processes by facilitating the sorting and concentration of cargo proteins within multivesicular bodies, which are essential for proper trafficking of proteins and lipids in cells. This function influences various cellular activities, including apoptosis and endocytosis, thereby impacting cell survival and communication. Alix interacts with several key proteins, including apoptosis-associated proteins like ALG-2 and PDCD6, as well as endosomal sorting complexes required for transport (ESCRT) proteins such as Tsg101 and CHMP4. Anti-Alix antibody (2H12) serves as an invaluable tool for researchers studying cellular dynamics and disease mechanisms, including viral pathogenesis through Alix′s association with HIV-1.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Alix Antibody (2H12) | sc-53539 | 200 µg/ml | $316.00 | |||
Alix Antibody (2H12): m-IgG Fc BP-HRP Bundle | sc-536983 | 200 µg Ab; 10 µg BP | $354.00 | |||
Alix Antibody (2H12): m-IgGκ BP-HRP Bundle | sc-534162 | 200 µg Ab; 40 µg BP | $354.00 | |||
Alix Antibody (2H12): m-IgG1 BP-HRP Bundle | sc-544939 | 200 µg Ab; 20 µg BP | $354.00 |