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Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10): sc-365160

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Datasheets
  • Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids near the N-terminus of ALDH6A1 of human origin
  • recommended for detection of ALDH6A1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10) for WB applications. These reagents are now offered in bundles with Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10) (see ordering information below).

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    SEE ALSO...

    ALDH6A1 Antibody (F-10) is a mouse monoclonal IgG2a antibody that detects ALDH6A1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ALDH6A1, also known as MMSDH or MMSADHA, is a 535 amino acid mitochondrial protein that plays a crucial role in the metabolism of various substrates, including valine and pyrimidines, by catalyzing the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. This enzymatic activity is vital for maintaining cellular homeostasis and detoxifying harmful aldehydes, particularly in the context of alcohol metabolism and lipid peroxidation. The localization of ALDH6A1 within the mitochondria is significant, as this placement allows for efficient processing of metabolic intermediates and contributes to overall energy production within the cell. ALDH6A1 antibody (F-10) enables researchers to gain insights into the functional dynamics of ALDH6A1 and its implications in metabolic disorders and cellular stress responses.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10)

    sc-365160
    200 µg/ml
    $322.00

    Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10): m-IgG Fc BP-HRP Bundle

    sc-537782
    200 µg Ab; 10 µg BP
    $361.00

    Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10): m-IgGκ BP-HRP Bundle

    sc-535165
    200 µg Ab; 40 µg BP
    $361.00

    Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10): m-IgG2a BP-HRP Bundle

    sc-548121
    200 µg Ab; 10 µg BP
    $361.00

    Aldehyde dehydrogenase 6-A1/ALDH6A1 (F-10) Neutralizing Peptide

    sc-365160 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-365160 P appropriate for?

    Asked by: Dr Ninau Qelp
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_12, d_30, h_8CST
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    Rated 5 out of 5 by from Positive band in WB in Jurkat whole cell lysatePositive band in WB in Jurkat whole cell lysate. -SCBT QC
    Date published: 2015-04-18
    Rated 5 out of 5 by from Good specificity in WB in human liver tissueGood specificity in WB in human liver tissue extract and C4 whole cell lysate. -SCBT QC
    Date published: 2015-02-08
    Rated 5 out of 5 by from Strong signal in WB in HepG2 whole cell lysateStrong signal in WB in HepG2 whole cell lysate. -SCBT QC
    Date published: 2014-11-26
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    Aldehyde dehydrogenase 6-A1/ALDH6A1 Antibody (F-10) is rated 5.0 out of 5 by 3.
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