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ALB Antibody (1D6) is a rat monoclonal IgG2b antibody engineered to recognize full-length purified mouse albumin (ALB), also known as serum albumin. ALB monoclonal antibody (1D6) is recommended for use in western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA) applications specifically in mouse samples. Albumin is the most abundant protein in blood plasma, playing a crucial role in maintaining osmotic pressure and serving as a carrier for various endogenous and exogenous substances. Structurally, albumin consists of three homologous domains, each containing multiple binding sites that facilitate the transport of fatty acids, hormones, bilirubin, and drugs, among other ligands. This intricate structure is essential for its function, allowing albumin to bind and release molecules efficiently, thereby regulating their availability and distribution within the body. Synthesized in the liver, albumin undergoes post-translational modifications that are vital for its stability and functionality in the bloodstream. The precise three-dimensional conformation of albumin is critical for its ability to interact with diverse ligands and maintain its structural integrity under varying physiological conditions. Mutations in the ALB gene can disrupt the protein′s structure, leading to disorders such as familial dysalbuminemic hyperthyroxinemia (FDH), which affects thyroid hormone binding. ALB (1D6) antibody is an essential tool for researchers studying albumin-related physiological processes and pathological conditions in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALB/Albumin Antibody (1D6) | sc-58687 | 100 µg/ml | $322.00 |