Akt2 Antibody (1G8C12): sc-81148
- Akt2 Antibody (1G8C12) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against a recombinant protein corresponding to amino acids 2-150 of Akt2 of human origin
- Anti-Akt2 Antibody (1G8C12) is recommended for detection of Akt2 of mouse, rat and human origin by WB and IP
- Anti-Akt2 Antibody (1G8C12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Akt2 Antibody (1G8C12) for WB applications. These reagents are now offered in bundles with Akt2 Antibody (1G8C12) (see ordering information below).
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Akt2 Antibody (1G8C12) is a mouse monoclonal IgG2b kappa light chain antibody that detects Akt2 in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP). Anti-Akt2 antibody (1G8C12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Akt2, a member of the serine/threonine kinase Akt family, plays a crucial role in cellular signaling pathways that regulate metabolism, cell growth, and survival. Specifically, Akt2 is activated by phosphatidylinositol 3-kinase (PI3K) in response to insulin and insulin-like growth factor 1 (IGF-1). This activation is essential for mediating glucose uptake and glycogen synthesis, making Akt2 a key player in metabolic regulation and energy homeostasis. Akt2′s ability to promote cell survival and inhibit apoptosis underscores its importance in various physiological processes, including adipocyte differentiation and muscle development. Understanding Akt2′s function and regulatory mechanisms is vital for exploring therapeutic strategies in metabolic disorders and cancer, where dysregulation of this pathway is often observed.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Akt2 Antibody (1G8C12) | sc-81148 | 200 µg/ml | $316.00 | |||
Akt2 Antibody (1G8C12): m-IgGκ BP-HRP Bundle | sc-521164 | 200 µg Ab, 40 µg BP | $354.00 | |||
Akt2 Antibody (1G8C12): m-IgG2b BP-HRP Bundle | sc-548868 | 200 µg Ab; 10 µg BP | $354.00 | |||
Akt2 Antibody (1G8C12) AC | sc-81148 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Akt2 Antibody (1G8C12) HRP | sc-81148 HRP | 200 µg/ml | $316.00 | |||
Akt2 Antibody (1G8C12) FITC | sc-81148 FITC | 200 µg/ml | $330.00 | |||
Akt2 Antibody (1G8C12) PE | sc-81148 PE | 200 µg/ml | $343.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 488 | sc-81148 AF488 | 200 µg/ml | $357.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 546 | sc-81148 AF546 | 200 µg/ml | $357.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 594 | sc-81148 AF594 | 200 µg/ml | $357.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 647 | sc-81148 AF647 | 200 µg/ml | $357.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 680 | sc-81148 AF680 | 200 µg/ml | $357.00 | |||
Akt2 Antibody (1G8C12) Alexa Fluor® 790 | sc-81148 AF790 | 200 µg/ml | $357.00 |