Akt1 Antibody (A-11): sc-377457
- Akt1 Antibody (A-11) is a mouse monoclonal IgG1 κ, cited in 35 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 443-479 near the C-terminus of Akt1 of human origin
- recommended for detection of Akt1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See Akt1 (B-1): sc-5298 for Akt1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Akt1 Antibody (A-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Akt1 Antibody (A-11) (see ordering information below).
QUICK LINKS
Akt1 Antibody (A-11) is a mouse monoclonal IgG1 antibody that detects Akt1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Akt1, also known as protein kinase B (PKB), plays a crucial role in cellular signaling pathways that regulate cell growth, survival, and metabolism, making Akt1 a key player in processes such as glucose metabolism and apoptosis. Akt1 is primarily located in the cytoplasm and can translocate to the plasma membrane upon activation, which is essential for mediating signals from growth factors like insulin and platelet-derived growth factor (PDGF). Upon activation, Akt1 phosphorylates various downstream targets, influencing numerous cellular processes, including protein synthesis and cell cycle progression. Akt1′s cellular location is crucial, as membrane translocation enables activation by phosphatidylinositol 3-kinase (PI3K), essential for growth factor signaling propagation. Anti-Akt1 antibody (A-11) serves as an invaluable tool for researchers studying the intricate signaling pathways that govern cell behavior and Akt1′s implications in various diseases, including cancer and metabolic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Akt1 Antibody (A-11) | sc-377457 | 200 µg/ml | $316.00 | |||
Akt1 Antibody (A-11): m-IgG Fc BP-HRP Bundle | sc-540721 | 200 µg Ab; 10 µg BP | $354.00 | |||
Akt1 Antibody (A-11): m-IgG1 BP-HRP Bundle | sc-542323 | 200 µg Ab; 20 µg BP | $354.00 | |||
Akt1 (A-11) Neutralizing Peptide | sc-377457 P | 100 µg/0.5 ml | $68.00 |