AKAP 8L Antibody (B-6): sc-376338
- AKAP 8L Antibody (B-6) is a mouse monoclonal IgG1 (lambda light chain) provided at 200 µg/ml
- specific for an epitope mapping between amino acids 617-647 at the C-terminus of AKAP 8L of human origin
- recommended for detection of AKAP 8L of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for AKAP 8L Antibody (B-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with AKAP 8L Antibody (B-6) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
AKAP 8L Antibody (B-6) is a mouse monoclonal IgG1 antibody that detects AKAP 8L in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). AKAP 8L, also known as HA95 or Helicase A-binding protein 95, is a crucial nuclear matrix protein that plays a significant role in cellular processes, particularly during mitosis. AKAP 8L is essential for proper deacetylation of Histone H3, a modification vital for chromatin remodeling and gene expression regulation during cell division. The interaction of AKAP 8L with AKAP 8 and histone deacetylase 3 (HDAC3) underscores AKAP 8L′s importance in maintaining chromosomal integrity and facilitating mitotic progression. By anchoring PKA to specific sites within the nucleus, AKAP 8L ensures precise regulation of signaling pathways, which is critical for normal cellular function and development. Anti-AKAP 8L antibody (B-6) serves as an invaluable tool for researchers studying the dynamics of cell division and the intricate signaling mechanisms that govern cellular behavior.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AKAP 8L Antibody (B-6) | sc-376338 | 200 µg/ml | $322.00 | |||
AKAP 8L Antibody (B-6): m-IgGλ BP-HRP Bundle | sc-522921 | 200 µg Ab, 40 µg BP | $361.00 | |||
AKAP 8L (B-6) Neutralizing Peptide | sc-376338 P | 100 µg/0.5 ml | $69.00 |