AIP5 Antibody (F-3): sc-390897
- AIP5 Antibody (F-3) is a mouse monoclonal IgG1 κ AIP5 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 88-312 within an internal region of AIP5 of human origin
- AIP5 Antibody (F-3) is recommended for detection of AIP5 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-AIP5 Antibody (F-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for AIP5 Antibody (F-3) for WB applications. These reagents are now offered in bundles with AIP5 Antibody (F-3) (see ordering information below).
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AIP5 Antibody (F-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects AIP5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AIP5 (F-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. AIP5 plays a crucial role in cellular processes by interacting with atrophin-1, particularly in the context of polyglutamine diseases, which are linked to neurodegenerative disorders. AIP5 is characterized by four WW domains, which are essential for protein-protein interactions, allowing AIP5 to bind to other proteins involved in signaling pathways and cellular regulation. The presence of a HECT domain in AIP5 indicates potential function as an E3 ubiquitin ligase, which is vital for tagging proteins for degradation, thus maintaining cellular homeostasis. Understanding AIP5 interactions and functions is important for elucidating mechanisms underlying diseases associated with protein misfolding and aggregation, making anti-AIP5 antibody (F-3) a valuable tool for researchers studying these critical biological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
AIP5 Antibody (F-3) References:
- Expression profiling and functional analysis of wnt signaling mechanisms in mesenchymal stem cells. | Etheridge, SL., et al. 2004. Stem Cells. 22: 849-60. PMID: 15342948
- Identification of novel spartin-interactors shows spartin is a multifunctional protein. | Milewska, M., et al. 2009. J Neurochem. 111: 1022-30. PMID: 19765186
- Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity. | Zaarour, RF., et al. 2012. PLoS One. 7: e37490. PMID: 22629406
- Gene methylation in gastric cancer. | Qu, Y., et al. 2013. Clin Chim Acta. 424: 53-65. PMID: 23669186
- Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer. | Wu, XQ., et al. 2013. Cell Signal. 25: 2462-8. PMID: 23993966
- Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization. | Xie, Y., et al. 2019. Nat Commun. 10: 5078. PMID: 31699995
- WWP, a new amino acid motif present in single or multiple copies in various proteins including dystrophin and the SH3-binding Yes-associated protein YAP65. | André, B. and Springael, JY. 1994. Biochem Biophys Res Commun. 205: 1201-5. PMID: 7802651
- The rsp5-domain is shared by proteins of diverse functions. | Hofmann, K. and Bucher, P. 1995. FEBS Lett. 358: 153-7. PMID: 7828727
- The WW domain: a signalling site in dystrophin? | Bork, P. and Sudol, M. 1994. Trends Biochem Sci. 19: 531-3. PMID: 7846762
- Identification of novel human WW domain-containing proteins by cloning of ligand targets. | Pirozzi, G., et al. 1997. J Biol Chem. 272: 14611-6. PMID: 9169421
- The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice. | Perry, WL., et al. 1998. Nat Genet. 18: 143-6. PMID: 9462742
- Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins. | Wood, JD., et al. 1998. Mol Cell Neurosci. 11: 149-60. PMID: 9647693
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AIP5 Antibody (F-3) | sc-390897 | 200 µg/ml | $322.00 | |||
AIP5 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-551153 | 200 µg Ab; 10 µg BP | $361.00 | |||
AIP5 Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-551152 | 200 µg Ab; 40 µg BP | $361.00 | |||
AIP5 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-551154 | 200 µg Ab; 20 µg BP | $361.00 | |||
AIP5 Antibody (F-3) AC | sc-390897 AC | 500 µg/ml, 25% agarose | $424.00 | |||
AIP5 Antibody (F-3) HRP | sc-390897 HRP | 200 µg/ml | $322.00 | |||
AIP5 Antibody (F-3) FITC | sc-390897 FITC | 200 µg/ml | $336.00 | |||
AIP5 Antibody (F-3) PE | sc-390897 PE | 200 µg/ml | $349.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 488 | sc-390897 AF488 | 200 µg/ml | $364.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 546 | sc-390897 AF546 | 200 µg/ml | $364.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 594 | sc-390897 AF594 | 200 µg/ml | $364.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 647 | sc-390897 AF647 | 200 µg/ml | $364.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 680 | sc-390897 AF680 | 200 µg/ml | $364.00 | |||
AIP5 Antibody (F-3) Alexa Fluor® 790 | sc-390897 AF790 | 200 µg/ml | $364.00 | |||
AIP5 (F-3) Neutralizing Peptide | sc-390897 P | 100 µg/0.5 ml | $69.00 |