AIF Antibody (B-9): sc-55519
- AIF Antibody (B-9) is a mouse monoclonal IgG2a κ, cited in 29 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of AIF of human origin
- Anti-AIF Antibody (B-9) is recommended for detection of AIF of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-AIF Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for AIF Antibody (B-9) for WB and IHC(P) applications. These reagents are now offered in bundles with AIF Antibody (B-9) (see ordering information below).
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AIF Antibody (B-9) is a mouse monoclonal IgG2a kappa light chain antibody raised against amino acids 1-300 mapping at the N-terminus of human Apoptosis-Inducing Factor (AIF), also known as AIFM1. Anti-AIF antibody (B-9) detects AIF proteins from mouse, rat, and human origins by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). AIF is a mitochondrial flavoprotein located in the intermembrane space of mitochondria, where AIF plays a crucial role in caspase-independent apoptosis. Upon apoptotic stimuli, AIF translocates from the mitochondria to the nucleus, inducing chromatin condensation and large-scale DNA fragmentation, which are key features of programmed cell death. The mitochondrial localization of AIF is important because AIF release links mitochondrial dysfunction to cell death mechanisms, contributing to various pathological conditions such as neurodegenerative diseases and cancer. Understanding AIF′s cellular location and function is significant for studying diseases where apoptosis is dysregulated. AIF monoclonal antibody (B-9) serves as an invaluable tool for researchers investigating mitochondrial biology and apoptosis by targeting the N-terminal region of AIF.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AIF Antibody (B-9) | sc-55519 | 200 µg/ml | $316.00 | |||
AIF Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-525630 | 200 µg Ab; 10 µg BP | $354.00 | |||
AIF Antibody (B-9): m-IgG2a BP-HRP Bundle | sc-546344 | 200 µg Ab; 10 µg BP | $354.00 | |||
AIF Antibody (B-9) AC | sc-55519 AC | 500 µg/ml, 25% agarose | $416.00 | |||
AIF Antibody (B-9) HRP | sc-55519 HRP | 200 µg/ml | $316.00 | |||
AIF Antibody (B-9) FITC | sc-55519 FITC | 200 µg/ml | $330.00 | |||
AIF Antibody (B-9) PE | sc-55519 PE | 200 µg/ml | $343.00 | |||
AIF Antibody (B-9) Alexa Fluor® 488 | sc-55519 AF488 | 200 µg/ml | $357.00 | |||
AIF Antibody (B-9) Alexa Fluor® 546 | sc-55519 AF546 | 200 µg/ml | $357.00 | |||
AIF Antibody (B-9) Alexa Fluor® 594 | sc-55519 AF594 | 200 µg/ml | $357.00 | |||
AIF Antibody (B-9) Alexa Fluor® 647 | sc-55519 AF647 | 200 µg/ml | $357.00 | |||
AIF Antibody (B-9) Alexa Fluor® 680 | sc-55519 AF680 | 200 µg/ml | $357.00 | |||
AIF Antibody (B-9) Alexa Fluor® 790 | sc-55519 AF790 | 200 µg/ml | $357.00 |