ADRM1 Antibody (F-12): sc-166754
- ADRM1 Antibody (F-12) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-205 mapping at the N-terminus of ADRM1 of human origin
- recommended for detection of ADRM1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ADRM1 Antibody (F-12) for WB and IHC(P) applications. These reagents are now offered in bundles with ADRM1 Antibody (F-12) (see ordering information below).
QUICK LINKS
ADRM1 Antibody (F-12) is a mouse monoclonal IgG2a antibody that detects ADRM1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ADRM1, also known as adhesion-regulating molecule 1, GP110, ARM-1, or Rpn13, is a 407 amino acid protein that plays a crucial role in cellular processes by localizing to both the nucleus and cytoplasm. ADRM1 is integral to the membrane and primarily involved in recruiting UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, thereby enhancing proteasome activity. ADRM1 mediates lymphocyte adhesion to endothelial cells, which is vital for lymphocyte homing and immune response. ADRM1 expression is induced by interferon-gamma in certain cancer cell lines and shows upregulation in various metastatic cells, indicating potential involvement in carcinogenesis. Two isoforms of ADRM1 arise from alternative splicing, contributing to functional diversity in different cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADRM1 Antibody (F-12) | sc-166754 | 200 µg/ml | $316.00 | |||
ADRM1 Antibody (F-12): m-IgG Fc BP-HRP Bundle | sc-540154 | 200 µg Ab; 10 µg BP | $354.00 | |||
ADRM1 Antibody (F-12): m-IgG2a BP-HRP Bundle | sc-546862 | 200 µg Ab; 10 µg BP | $354.00 |