ADRM1 Antibody (C-7): sc-376221
- ADRM1 Antibody (C-7) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-29 at the N-terminus of ADRM1 of human origin
- recommended for detection of ADRM1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ADRM1 Antibody (C-7) for WB and IHC(P) applications. These reagents are now offered in bundles with ADRM1 Antibody (C-7) (see ordering information below).
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ADRM1 Antibody (C-7) is a mouse monoclonal IgG1 antibody that detects ADRM1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ADRM1, also known as adhesion-regulating molecule 1, GP110, ARM-1, or Rpn13, is a 407 amino acid protein that plays a crucial role in cellular processes by localizing to both the nucleus and cytoplasm. ADRM1 is integral to the membrane and primarily involved in recruiting UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, thereby enhancing UCH-L5 activity and facilitating ubiquitinated protein degradation. ADRM1 functions in lymphocyte adhesion within endothelial cells, which is vital for lymphocyte homing and immune response. ADRM1 expression is induced by interferon-gamma in certain cancer cell lines and upregulated in various metastatic cells, indicating potential involvement in carcinogenesis. Two isoforms of ADRM1 arise from alternative splicing, which may contribute to functional diversity in different cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADRM1 Antibody (C-7) | sc-376221 | 200 µg/ml | $322.00 | |||
ADRM1 Antibody (C-7): m-IgG Fc BP-HRP Bundle | sc-540530 | 200 µg Ab; 10 µg BP | $361.00 | |||
ADRM1 Antibody (C-7): m-IgG1 BP-HRP Bundle | sc-542186 | 200 µg Ab; 20 µg BP | $361.00 | |||
ADRM1 (C-7) Neutralizing Peptide | sc-376221 P | 100 µg/0.5 ml | $69.00 |