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AdoMetDC Antibody (H-9) is a mouse monoclonal IgG1 antibody that detects AdoMetDC in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). AdoMetDC, or adenylmethionine decarboxylase 1, is a crucial enzyme in the polyamine biosynthesis pathway, consisting of 334 amino acids. AdoMetDC (H-9) monoclonal antibody enables research into cellular growth and proliferation by detecting the enzyme that catalyzes the conversion of S-adenosyl-L-methionine into a key intermediate essential for polyamine synthesis, which supports cell division and differentiation. AdoMetDC is initially synthesized as an inactive proenzyme that undergoes self-maturation to produce two distinct subunits, α and β, which then assemble into an active heterotetramer. Polyamines such as putrescine enhance both the processing of the proenzyme and catalytic function, while inhibitors like iodoacetic acid can suppress AdoMetDC activity. AdoMetDC′s role in modulating polyamine levels highlights its significance in cellular processes and cancer biology, making anti-AdoMetDC antibody (H-9) an invaluable research tool for studying these pathways.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AdoMetDC Antibody (H-9) | sc-390073 | 200 µg/ml | $316.00 | |||
AdoMetDC Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-540751 | 200 µg Ab; 10 µg BP | $354.00 | |||
AdoMetDC Antibody (H-9): m-IgG1 BP-HRP Bundle | sc-542347 | 200 µg Ab; 20 µg BP | $354.00 | |||
AdoMetDC (H-9) Neutralizing Peptide | sc-390073 P | 100 µg/0.5 ml | $68.00 |