ACYP2 Antibody (B-3): sc-398298
- ACYP2 Antibody (B-3) is a mouse monoclonal IgG2b κ ACYP2 antibody provided at 200 µg/ml
- raised against amino acids 1-99 representing full length ACYP2 of human origin
- ACYP2 Antibody (B-3) is recommended for detection of muscle ACYP2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ACYP2 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ACYP2 Antibody (B-3) for WB applications. These reagents are now offered in bundles with ACYP2 Antibody (B-3) (see ordering information below).
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ACYP2 Antibody (B-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects ACYP2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACYP2 (B-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ACYP2, also known as muscle acylphosphatase, plays a crucial role in muscle metabolism by hydrolyzing acylphosphate compounds, which are important for energy production and muscle contraction. ACYP2′s proper function is vital for maintaining muscle health and preventing metabolic disorders. ACYP2′s structure, consisting of a five-stranded antiparallel beta-sheet and two parallel alpha-helices, is essential for enzymatic activity and stability. Disruptions in ACYP2′s structural integrity can lead to misfolding and aggregation, which are implicated in various protein deposition diseases. Understanding ACYP2′s structural characteristics not only aids in elucidating biological function but also provides insights into the mechanisms underlying muscle-related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACYP2 Antibody (B-3) References:
- Mutational analysis of the propensity for amyloid formation by a globular protein. | Chiti, F., et al. 2000. EMBO J. 19: 1441-9. PMID: 10747012
- Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformation. | Chiti, F., et al. 2001. Protein Sci. 10: 879-86. PMID: 11274479
- Folding and aggregation are selectively influenced by the conformational preferences of the alpha-helices of muscle acylphosphatase. | Taddei, N., et al. 2001. J Biol Chem. 276: 37149-54. PMID: 11479314
- Kinetic partitioning of protein folding and aggregation. | Chiti, F., et al. 2002. Nat Struct Biol. 9: 137-43. PMID: 11799398
- Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases. | Chiti, F., et al. 2002. Proc Natl Acad Sci U S A. 99 Suppl 4: 16419-26. PMID: 12374855
- The molecular basis of amyloidosis. | Serpell, LC., et al. 1997. Cell Mol Life Sci. 53: 871-87. PMID: 9447239
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACYP2 Antibody (B-3) | sc-398298 | 200 µg/ml | $316.00 | |||
ACYP2 Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-530746 | 200 µg Ab; 10 µg BP | $354.00 | |||
ACYP2 Antibody (B-3): m-IgGκ BP-HRP Bundle | sc-524281 | 200 µg Ab, 40 µg BP | $354.00 | |||
ACYP2 Antibody (B-3): m-IgG2b BP-HRP Bundle | sc-550219 | 200 µg Ab; 10 µg BP | $354.00 | |||
ACYP2 Antibody (B-3) AC | sc-398298 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ACYP2 Antibody (B-3) HRP | sc-398298 HRP | 200 µg/ml | $316.00 | |||
ACYP2 Antibody (B-3) FITC | sc-398298 FITC | 200 µg/ml | $330.00 | |||
ACYP2 Antibody (B-3) PE | sc-398298 PE | 200 µg/ml | $343.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 488 | sc-398298 AF488 | 200 µg/ml | $357.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 546 | sc-398298 AF546 | 200 µg/ml | $357.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 594 | sc-398298 AF594 | 200 µg/ml | $357.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 647 | sc-398298 AF647 | 200 µg/ml | $357.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 680 | sc-398298 AF680 | 200 µg/ml | $357.00 | |||
ACYP2 Antibody (B-3) Alexa Fluor® 790 | sc-398298 AF790 | 200 µg/ml | $357.00 |