ACSVL6 Antibody (C-8): sc-377374
- ACSVL6 Antibody (C-8) is a mouse monoclonal IgG2a κ ACSVL6 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 587-632 mapping near the C-terminus of ACSVL6 of human origin
- ACSVL6 Antibody (C-8) is recommended for detection of ACSVL6 of human origin by WB, IP, IF and ELISA
- Anti-ACSVL6 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ACSVL6 Antibody (C-8) for WB applications. These reagents are now offered in bundles with ACSVL6 Antibody (C-8) (see ordering information below).
QUICK LINKS
ACSVL6 Antibody (C-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects ACSVL6 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACSVL6 (C-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ACSVL6, a member of the acyl-coenzyme A synthetase (ACS) family, plays a crucial role in fatty acid metabolism by catalyzing the activation of long-chain and very long-chain fatty acids, which is essential for their subsequent utilization in various metabolic pathways. ACSVL6 is part of a larger family characterized by their preference for different fatty acid chain lengths, with ACSVL6 specifically classified under the very long-chain acyl-CoA synthetases. The ACSVL family, which includes six members identified as solute carrier family 27A (SLC27A) gene products, is vital for the transport of fatty acids across the plasma membrane, facilitating their entry into cells for energy production and biosynthesis. Unique expression patterns of ACSVLs in key organs such as adipose tissue, liver, heart, and kidney highlight their importance in maintaining metabolic homeostasis and energy balance.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACSVL6 Antibody (C-8) References:
- Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. | Abumrad, N., et al. 1999. Biochim Biophys Acta. 1441: 4-13. PMID: 10526223
- Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target. | Martin, G., et al. 2000. J Biol Chem. 275: 12612-8. PMID: 10777552
- The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression. | Martin, G., et al. 2000. Genomics. 66: 296-304. PMID: 10873384
- Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans. | Binnert, C., et al. 2000. Am J Physiol Endocrinol Metab. 279: E1072-9. PMID: 11052962
- Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. | Watkins, PA., et al. 2007. J Lipid Res. 48: 2736-50. PMID: 17762044
- Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. | Schaffer, JE. and Lodish, HF. 1994. Cell. 79: 427-36. PMID: 7954810
- A family of fatty acid transporters conserved from mycobacterium to man. | Hirsch, D., et al. 1998. Proc Natl Acad Sci U S A. 95: 8625-9. PMID: 9671728
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACSVL6 Antibody (C-8) | sc-377374 | 200 µg/ml | $322.00 | |||
ACSVL6 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-530016 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACSVL6 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-523301 | 200 µg Ab, 40 µg BP | $361.00 | |||
ACSVL6 Antibody (C-8): m-IgG2a BP-HRP Bundle | sc-547420 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACSVL6 Antibody (C-8) AC | sc-377374 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ACSVL6 Antibody (C-8) HRP | sc-377374 HRP | 200 µg/ml | $322.00 | |||
ACSVL6 Antibody (C-8) FITC | sc-377374 FITC | 200 µg/ml | $336.00 | |||
ACSVL6 Antibody (C-8) PE | sc-377374 PE | 200 µg/ml | $349.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 488 | sc-377374 AF488 | 200 µg/ml | $364.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 546 | sc-377374 AF546 | 200 µg/ml | $364.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 594 | sc-377374 AF594 | 200 µg/ml | $364.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 647 | sc-377374 AF647 | 200 µg/ml | $364.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 680 | sc-377374 AF680 | 200 µg/ml | $364.00 | |||
ACSVL6 Antibody (C-8) Alexa Fluor® 790 | sc-377374 AF790 | 200 µg/ml | $364.00 |