ACOT11 Antibody (J4B2) is a mouse monoclonal IgG2b antibody that detects ACOT11 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). ACOT11, also known as acyl-CoA thioesterase 11, BFIT, KIAA0707, or THEA, is a 607 amino acid protein that plays a crucial role in lipid metabolism by catalyzing the hydrolysis of acyl-CoA to produce coenzyme A and free fatty acids. This enzymatic activity is vital for regulating intracellular levels of fatty acids and acyl-CoAs, which are essential for various cellular processes, including energy production and membrane synthesis. ACOT11 is predominantly localized in the cytoplasm and features one START domain and two acyl coenzyme A hydrolase domains, which are important for catalytic function. ACOT11 is expressed in multiple tissues, with two alternatively spliced isoforms found in liver, testis, spleen, brain, lung, stomach, kidney, and uterus, highlighting diverse physiological roles. Anti-ACOT11 antibody (J4B2) is an invaluable tool for researchers studying lipid metabolism and related pathways, providing insights into ACOT11′s function and implications in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACOT11 Antibody (J4B2) | sc-135626 | 100 µg/ml | $316.00 |