Nicotinic Acetylcholine Receptor delta/CHRND Antibody (139): sc-65807
- Nicotinic Acetylcholine Receptor delta/CHRND Antibody (139) is a rat monoclonal IgG2a provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChRδ of Torpedo origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor delta/CHRND Antibody (139). This work is in progress.
AChRδ Antibody (139) is a rat monoclonal IgG2a antibody that detects AChRδ in Torpedo species through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). AChRδ, also known as CMS2A, FCCMS, SCCMS, or CHRND, is a 517 amino acid multi-pass membrane protein that plays a crucial role in neuromuscular transmission by forming part of the nicotinic acetylcholine receptor complex. This receptor is essential for muscle contraction, as AChRδ mediates fast synaptic transmission at the neuromuscular junction by allowing cation influx upon acetylcholine binding. Proper functioning of AChRδ is vital, as mutations or dysfunctions are associated with severe neuromuscular disorders, including lethal type multiple pterygium syndrome and congenital myasthenic syndromes, both slow-channel and fast-channel types. Localization of AChRδ at the postsynaptic membrane ensures effective response to neurotransmitter release, facilitating rapid communication between nerve and muscle cells. Anti-AChRδ antibody (139) enables researchers to gain insights into neuromuscular signaling dynamics and underlying mechanisms of related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor delta/CHRND Antibody (139) | sc-65807 | 200 µg/ml | $316.00 |