Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
AChRα9 Antibody (8E4) is a high quality monoclonal AChR alpha 9 antibody (also designated CHRNA9 antibody, or Nicotinic Acetylcholine Receptor alpha 9 antibody) suitable for the detection of the AChR alpha 9 protein of mouse, rat and human origin. AChRα9 Antibody (8E4) is available as the non-conjugated anti-AChR alpha 9 antibody. Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. AChRα9 is the only AChR found in cochlear hair cells. In adult rat cochlear outer hair cells (OHCs), AChRα9 is expressed primarily in basal regions, where it is a component of the cholinergic receptor, while in inner hair cells (IHCs), it is expressed primarily in apical regions. The α9 subunit mediates efferent synaptic transmission between cholinergic olivocochlear fibers and OHCs. One of the main functions of the AChRα9 channel is to provide a pathway for calcium ion influx. AChRα9 may also influence the arrival of efferent axons.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.