Ac-MMP9 Antibody (4A3): sc-21736
- Ac-MMP9 Antibody (4A3) is a mouse monoclonal IgG1 κ Ac-MMP9 antibody, cited in 10 publications, provided at 200 µg/ml
- raised against acetylated amino acids 107-115 of Ac-MMP-9 of human origin
- recommended for detection of acetylated MMP-9 of human origin by WB, IF and IHC(P); non cross-reactive with non-acetylated MMP-9 or other lysine acetylation sites
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Ac-MMP9 Antibody (4A3) for WB and IHC(P) applications. These reagents are now offered in bundles with Ac-MMP9 Antibody (4A3) (see ordering information below).
Ac-MMP-9 Antibody (4A3) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect acetylated matrix metalloproteinase-9 (Ac-MMP-9), a key enzyme involved in the degradation of extracellular matrix components. Anti-Ac-MMP-9 antibody (4A3) is raised against a specific acetylated epitope encompassing amino acids 107-115 of human Ac-MMP-9, allowing for the selective recognition of the acetylated form of MMP-9. Matrix metalloproteinase-9 plays a significant role in various physiological and pathological processes, including tissue remodeling, angiogenesis, and inflammation, by breaking down proteins such as collagen, gelatin, fibronectin, and laminin. The acetylation of MMP-9 is a crucial post-translational modification that regulates enzymatic activity, stability, and interaction with other cellular proteins, thereby influencing function in cellular processes and disease progression. Anti-Ac-MMP-9 antibody (4A3) specifically recognizes the acetylated form of MMP-9 in human samples and does not cross-react with non-acetylated MMP-9 or other lysine acetylation sites, ensuring precise detection in various experimental settings. Ac-MMP-9 monoclonal antibody (4A3) is recommended for applications including western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP), making this tool valuable for researchers investigating the regulation and role of Ac-MMP-9 in conditions such as cancer metastasis, arthritis, and cardiovascular diseases. By enabling the targeted detection of acetylated MMP-9, anti-Ac-MMP-9 antibody (4A3) facilitates a deeper understanding of the molecular mechanisms governing extracellular matrix remodeling and its impact on disease mechanisms.
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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ac-MMP9 Antibody (4A3) | sc-21736 | 200 µg/ml | $322.00 | |||
Ac-MMP9 Antibody (4A3): m-IgG Fc BP-HRP Bundle | sc-538910 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ac-MMP9 Antibody (4A3): m-IgG1 BP-HRP Bundle | sc-541143 | 200 µg Ab; 20 µg BP | $361.00 |