Abi-2 Antibody (B-8): sc-271717
- Abi-2 Antibody (B-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 271-320 mapping within an internal region of Abi-2 of human origin
- recommended for detection of Abi-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Abi-2 Antibody (B-8) for WB and IHC(P) applications. These reagents are now offered in bundles with Abi-2 Antibody (B-8) (see ordering information below).
Abi-2 Antibody (B-8) is a mouse monoclonal IgG1 antibody that detects Abi-2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Abi-2, a member of the Abl interactor protein family, plays a crucial role in regulating cell motility by modulating actin polymerization in cellular structures such as lamellipodia and filopodia, which are essential for cell movement and shape changes. This regulation is particularly important in processes such as wound healing and immune responses, where precise cell migration is necessary. The interaction of Abi-2 with the Abl tyrosine kinase enhances its activity, thereby influencing downstream signaling pathways that govern cell growth and transformation. Notably, dysregulation of these pathways can lead to various pathologies, including cancer, making Abi-2 a significant protein in the study of oncogenic processes. Anti-Abi-2 antibody (B-8) serves as an invaluable tool for researchers investigating the functional dynamics of Abi-2 in different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Abi-2 Antibody (B-8) | sc-271717 | 200 µg/ml | $316.00 | |||
Abi-2 Antibody (B-8): m-IgG Fc BP-HRP Bundle | sc-540257 | 200 µg Ab; 10 µg BP | $354.00 | |||
Abi-2 Antibody (B-8): m-IgG1 BP-HRP Bundle | sc-542004 | 200 µg Ab; 20 µg BP | $354.00 |