ABCG2 Antibody (6D170): sc-69989
- ABCG2 Antibody (6D170) is a mouse monoclonal IgG2a, cited in 6 publications, provided at 100 µg/ml
- raised against amino acids 221-394 of ABCG2 of mouse origin
- recommended for detection of ABCG2 of mouse, rat and human origin by WB, IP, IF and FCM
- See ABCG2 (B-1): sc-377176 for ABCG2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ABCG2 Antibody (6D170). This work is in progress.
ABCG2 Antibody (6D170) is a mouse monoclonal IgG2a antibody that detects ABCG2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). ABCG2, also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1), plays a crucial role in transporting various molecules across cellular membranes, utilizing energy derived from ATP hydrolysis. Anti-ABCG2 antibody (6D170) recognizes a protein significant for conferring resistance to chemotherapeutic agents, including anthracyclines and topotecan, which poses challenges in cancer treatment. ABCG2 maintains the side population (SP) phenotype in stem cells, highlighting importance as a stem cell marker. ABCG2 is predominantly expressed in placenta, liver, intestine, and various stem cells, where ABCG2 functions to protect cells by expelling toxins and regulating stem cell differentiation. N-linked glycosylation and potential dimerization in vivo can influence ABCG2 functional properties and interactions with other proteins. Anti-ABCG2 antibody (6D170) serves as an invaluable tool for researchers studying drug resistance mechanisms and stem cell biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ABCG2 Antibody (6D170) | sc-69989 | 100 µg/ml | $316.00 |