8-OHdG Antibody (F-12): sc-393870
- 8-OHdG Antibody (F-12) is a mouse monoclonal IgM κ, cited in 6 publications, provided at 200 µg/ml
- raised against 8-Hydroxy-2′-deoxyguanosine (8-OHdG)-BCP conjugate of synthetic origin
- recommended for detection of 8-OHdG (8-Hydroxy-2′-deoxyguanosine) by IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for 8-OHdG Antibody (F-12). This work is in progress.
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8-OHdG Antibody (F-12) is a mouse monoclonal IgM antibody that detects 8-hydroxy-2′-deoxyguanosine in non-species reactive samples by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). 8-hydroxy-2′-deoxyguanosine is a critical marker of oxidative DNA damage, which plays a significant role in the development of various diseases, including cancer. 8-hydroxy-2′-deoxyguanosine forms when reactive oxygen and nitrogen species, such as hydroxyl radicals and peroxynitrite, modify DNA, leading to mutations that can disrupt normal cellular functions. 8-hydroxy-2′-deoxyguanosine in cells serves as an important indicator of oxidative stress and DNA integrity, making anti-8-hydroxy-2′-deoxyguanosine antibody (F-12) a valuable tool for researchers studying mutagenesis mechanisms and cellular response to DNA damage. Anti-8-hydroxy-2′-deoxyguanosine antibody (F-12) helps scientists gain insights into oxidative damage in biological samples, enhancing understanding of disease progression and potential therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-OHdG Antibody (F-12) | sc-393870 | 200 µg/ml | $322.00 |