podoplanin Antibody (E-1): sc-376695
- podoplanin Antibody (E-1) is a mouse monoclonal IgG2a κ, cited in 17 publications, provided at 200 µg/ml
- raised against amino acids 1-162 representing full length podoplanin of human origin
- podoplanin Antibody (E-1) is recommended for detection of podoplanin of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-podoplanin Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for podoplanin Antibody (E-1) for WB and IHC(P) applications. These reagents are now offered in bundles with podoplanin Antibody (E-1) (see ordering information below).
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SEE ALSO...
Podoplanin Antibody (E-1) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect Podoplanin, also known as glycoprotein 38 (gp38), T1-alpha, Aggrus, or PA2.26 antigen, in human samples using western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA) techniques. Anti-podoplanin antibody (E-1) targets amino acids 1-162 of the full-length human podoplanin protein, ensuring exceptional affinity and specificity. Podoplanin is a type I transmembrane glycoprotein that undergoes critical post-translational modifications, including extensive glycosylation, which are essential for its role in cell adhesion, migration, and signaling pathways. These glycosylation events are vital for podoplanin′s interactions with other proteins and proper localization within the cell membrane, thereby influencing processes such as lymphangiogenesis and immune cell trafficking. Located primarily in stromal cells of peripheral lymphoid tissues and thymic epithelial cells, podoplanin is crucial for maintaining the structural integrity and unique morphology of podocytes in the kidneys. Podoplanin (E-1) antibody enables detailed studies of its involvement in immune responses, lymphatic development, and renal function. Podoplanin monoclonal antibody (E-1) is available in both non-conjugated form and a variety of conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, providing versatility for diverse experimental applications. Anti-podoplanin antibody (E-1) has proven effectiveness in the Puromycin aminonucleoside nephrosis (PAN) rat model, highlighting utility in researching minimal change nephropathy and related kidney pathologies. Podoplanin (E-1) monoclonal antibody is an invaluable tool for researchers investigating the multifaceted roles of podoplanin in cellular structure and function within the immune and renal systems.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
podoplanin Antibody (E-1) | sc-376695 | 200 µg/ml | $322.00 | |||
podoplanin Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-529924 | 200 µg Ab; 10 µg BP | $361.00 | |||
podoplanin Antibody (E-1): m-IgGκ BP-HRP Bundle | sc-523049 | 200 µg Ab, 40 µg BP | $361.00 | |||
podoplanin Antibody (E-1): m-IgG2a BP-HRP Bundle | sc-547401 | 200 µg Ab; 10 µg BP | $361.00 | |||
podoplanin Antibody (E-1) AC | sc-376695 AC | 500 µg/ml, 25% agarose | $424.00 | |||
podoplanin Antibody (E-1) HRP | sc-376695 HRP | 200 µg/ml | $322.00 | |||
podoplanin Antibody (E-1) FITC | sc-376695 FITC | 200 µg/ml | $336.00 | |||
podoplanin Antibody (E-1) PE | sc-376695 PE | 200 µg/ml | $349.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 488 | sc-376695 AF488 | 200 µg/ml | $364.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 546 | sc-376695 AF546 | 200 µg/ml | $364.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 594 | sc-376695 AF594 | 200 µg/ml | $364.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 647 | sc-376695 AF647 | 200 µg/ml | $364.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 680 | sc-376695 AF680 | 200 µg/ml | $364.00 | |||
podoplanin Antibody (E-1) Alexa Fluor® 790 | sc-376695 AF790 | 200 µg/ml | $364.00 |