Date published: 2025-9-8

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P-Selectin/CD62P/SELP 항체 (CTB201): sc-8419

4.8(16)
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데이터 시트
  • P-Selectin/CD62P/SELP 항체 CTB201 는 마우스 monoclonal IgG1 κ P-Selectin/CD62P/SELP 항체, 50간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • 유전자침묵제품은 비영리적인용도나 연구에만 사용가능합니다 자세한 정보보기.
  • P-Selectin/CD62P/SELP 항체 (CTB201)는 WB, IP, IF, IHC(P) and FCM으로 mouse, rat and human유래의 P-Selectin 를 감지하는 데에 추천한다.
  • IP를 위해 agarose (sc-8419 AC), 500 µg/ml, 25% agarose; 또는 IF, IHC(P) and FCM를 위해 phycoerythrin (sc-8419 PE) or FITC (sc-8419 FITC), 200 µg/ml에결합된 P-Selectin/CD62P/SELP 항체 (CTB201)를 제공한다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • P-Selectin/CD62P/SELP (CTB201): sc-8419무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 는 P-Selectin/CD62P/SELP 항체 (CTB201) 가 WB and IHC(P) 에 응용될 때 우선으로 사용하는 이차 항체 검사 시약입니다.이 시약은P-Selectin/CD62P/SELP 항체(CTB201) 와 세트로 제공드립니다. (아래의 주문 정보를 참고해 주시길 바랍니다)

빠른 링크

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P-셀렉틴 항체(CTB201)는 마우스, 쥐, 인간에서 유래된 P-셀렉틴 단백질을 웨스턴 블롯(WB), 면역침전법(IP), 면역형광법(IF), 파라핀 포매 절편을 이용한 면역조직화학(IHCP), 유세포분석법(FCM)을 통해 검출하는 마우스 단일클론 IgG1 카파 경쇄 항체입니다. P-셀렉틴 항체(CTB201)는 비접합 형태와 아가로스, 피코에리틴(PE), 플루오레세인 이소티오시아네이트(FITC), 다중 알렉사 플루오르® 접합체를 포함한 다양한 접합 형태로 제공되어 다양한 실험적 요구에 대한 다목적성을 제공합니다. GMP-140 또는 CD62P로도 알려진 P-셀렉틴은 백혈구가 활성화된 내피세포와 혈소판에 부착하는 것을 매개함으로써 염증 반응에 중요한 역할을 하는데, 이는 손상 부위나 감염 부위에 면역 세포를 모집하는 데 필수적입니다. P-셀렉틴은 주로 활성화된 혈소판과 내피세포의 표면에 위치하며, 여기서 P-셀렉틴은 면역 반응의 중요한 단계인 백혈구의 구름과 부착을 촉진합니다. P-셀렉틴의 적절한 기능은 혈관 완전성을 유지하고 효과적인 면역 감시를 보장하는 데 필수적이며, 따라서 P-셀렉틴은 염증과 심혈관 질환 연구의 중요한 표적이 되고 있습니다. 항-P-셀렉틴 항체(CTB201)는 이러한 과정을 연구하고 다양한 병리의 근본적인 메커니즘을 이해하는 데 매우 유용한 도구입니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

P-Selectin/CD62P/SELP 항체 (CTB201) 참고문헌:

  1. P-셀렉틴: 심혈관 질환, 염증 및 종양 전이에 대한 일반적인 치료 표적.  |  Ludwig, RJ., et al. 2007. Expert Opin Ther Targets. 11: 1103-17. PMID: 17665981
  2. 분자 영상에서 P-셀렉틴 부착 분자를 표적으로 하는 것: 심혈관 질환에서 염증의 중요한 영상 바이오마커로서의 P-셀렉틴 발현.  |  Perkins, LA., et al. 2019. J Nucl Med. 60: 1691-1697. PMID: 31601694
  3. 폐쇄성 수면 무호흡증 환자에서 순환하는 P-셀렉틴 당단백질 리간드 1과 P-셀렉틴 수치.  |  Horváth, P., et al. 2020. Lung. 198: 173-179. PMID: 31897593
  4. P-셀렉틴 표적 RAGE-shRNA 리포플렉스는 죽상동맥경화증 관련 염증을 완화합니다.  |  Mocanu, CA., et al. 2021. J Control Release. 338: 754-772. PMID: 34530051
  5. 셀렉틴 리간드.  |  Varki, A. 1994. Proc Natl Acad Sci U S A. 91: 7390-7. PMID: 7519775
  6. 셀렉틴-탄수화물 상호작용에 의해 매개되는 백혈구 이동.  |  McEver, RP., et al. 1995. J Biol Chem. 270: 11025-8. PMID: 7538108
  7. L-셀렉틴의 세포질 도메인은 알파-액티닌을 통해 세포골격 단백질과 상호작용합니다: 미세 융모에서 수용체의 위치는 알파-액티닌과의 상호작용을 필요로 하지 않습니다.  |  Pavalko, FM., et al. 1995. J Cell Biol. 129: 1155-64. PMID: 7538138
  8. 셀렉틴: 혈관 부착 분자.  |  Tedder, TF., et al. 1995. FASEB J. 9: 866-73. PMID: 7542213
  9. 셀렉틴-탄수화물 상호 작용 및 염증 반응의 시작.  |  Lasky, LA. 1995. Annu Rev Biochem. 64: 113-39. PMID: 7574477
  10. P- 및 E- 셀렉틴이 모두 결핍된 마우스에서 감염에 대한 감수성 및 조혈 변화.  |  Frenette, PS., et al. 1996. Cell. 84: 563-74. PMID: 8598043
  11. 고내피 정맥으로의 혈소판 매개 림프구 전달.  |  Diacovo, TG., et al. 1996. Science. 273: 252-5. PMID: 8662511
  12. 두 개의 셀렉틴이 황산염에 수렴합니다. 백혈구 부착.  |  Rosen, SD. and Bertozzi, CR. 1996. Curr Biol. 6: 261-4. PMID: 8805242

주문정보

제품명카탈로그 번호 단위가격수량관심품목

P-Selectin/CD62P/SELP 항체 (CTB201)

sc-8419
200 µg/ml
$316.00

P-Selectin/CD62P/SELP (CTB201): m-IgG Fc BP-HRP 번들

sc-526522
200 µg Ab; 10 µg BP
$354.00

P-Selectin/CD62P/SELP (CTB201): m-IgG1 BP-HRP 번들

sc-531895
200 µg Ab; 20 µg BP
$354.00

P-Selectin/CD62P/SELP 항체 (CTB201) AC

sc-8419 AC
500 µg/ml, 25% agarose
$416.00

P-Selectin/CD62P/SELP 항체 (CTB201) FITC

sc-8419 FITC
200 µg/ml
$330.00

P-Selectin/CD62P/SELP 항체 (CTB201) PE

sc-8419 PE
200 µg/ml
$343.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 488

sc-8419 AF488
200 µg/ml
$357.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 546

sc-8419 AF546
200 µg/ml
$357.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 594

sc-8419 AF594
200 µg/ml
$357.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 647

sc-8419 AF647
200 µg/ml
$357.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 680

sc-8419 AF680
200 µg/ml
$357.00

P-Selectin/CD62P/SELP 항체 (CTB201) Alexa Fluor® 790

sc-8419 AF790
200 µg/ml
$357.00

Can this antibody work on western blots of mouse kidney, lung or liver tissue? Anti-P-Selectin/CD62P/SELP Antibody (CTB201): sc-8419

Asked by: ssun
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-01-20

Can you maybe provide any information regarding the isoelectric point of this antibody or guide me in the right direction, please?

Asked by: Riaan
Thank you for your question. We do not characterize the isoelectric point for any of our antibodies. The isoelectric point (pI) of IgG is found in the range of 6.4 to 9.0 [1]. References: [1] Li G, Stewart R, Conlan B, Gilbert A, Roerth P, Nair H. Purification of human immunoglobulin G: A new approach to plasma fractionation. Vox Sanguinis (2002) 83, 332-338.
Answered by: Technical Support
Date published: 2019-07-12

For the dye conjugated antibodies (eg. P-selectin-FITC), will further conjugation still be available on that antibody? ie. does the antibody still have primary NH2 groups for other conjugation reactions?

Asked by: mich77
Thank you for your question. Most reactive/readily available primary amines have most likely have been conjugated. We can not say definitely, but there may be some available. However, we would not recommend attempting additional conjugation of the antibody since the antibody conjugates are provided with a stabilizing protein (gelatin) which would interfere with the conjugation.
Answered by: Technical Support
Date published: 2019-06-16

I purchased 4 antibodies against human PECAM, VE-Cadherin, Ang-2 and P-selectin for IF of endothelial cells, all first three antibodies worked well, but the P-selectin ( sc-8419) did not worked. I used same secondary antibodies for all of them.

Asked by: HamidehYaD
Thank you for your question. We are sorry to hear that you are not getting the expected result with one of our antibodies. Please contact our Technical Service by phone, email or by Live Chat. They will help you figure out how to resolve the issue and provide an appropriate replacement free of charge if the original antibody does not work.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-30

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with P-Selectin Antibody (CTB201): sc-8419?

Asked by: Trav11
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGκ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Service 11
Date published: 2017-01-17

Does P-Selectin Antibody (CTB201): sc-8419 react with canine samples?

Asked by: Trav11
Thank you for your question. For additional species reactivity not listed on our website, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or by using the Live Chat function on our website and we will be more than happy to run sequence analysis for your species of interest.
Answered by: Technical Support 5
Date published: 2017-01-16
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Rated 1 out of 5 by from Tested on HFFF by FACSThis antibody was tested on HFFF cells by FACS and did not give a signal, even at dilution 1:25
Date published: 2018-11-19
Rated 5 out of 5 by from ExcellentAntibodies are used in human platelet extract, which are better than what I ordered from other suppliers and strong signals are diluted at high concentrations
Date published: 2017-10-31
Rated 5 out of 5 by from clear bandObtained a single clear band in Western Blot with 293T cells.
Date published: 2017-02-25
Rated 5 out of 5 by from Superb dataWorks well for FCM, IF and western blot applications
Date published: 2017-01-24
Rated 5 out of 5 by from Great monoclonal choice for P-SelectinStrong and specific, it's a great choice for IHC(P), FCM, IF or WB applications.
Date published: 2017-01-17
Rated 5 out of 5 by from Works very goodexcellent antibody, works by western blot at 1:1000 for both mouse and human lysates
Date published: 2016-12-17
Rated 5 out of 5 by from very goodWe often use P-Selectin antibody,used for Western blot detection of platelet extraction,always use domestic brands antibody, are colleagues recommend Santa monoclonal antibodies,Effect is very good.
Date published: 2016-12-17
Rated 5 out of 5 by from Use this routinely in WB and works wellUse this routinely in WB and works well.
Date published: 2015-07-10
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P-Selectin/CD62P/SELP 항체 (CTB201) is rated 4.8 out of 5 by 16.
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