FGF-3 Antibody (MSD 1): sc-135
- FGF-3 Antibody (MSD 1) is a mouse monoclonal IgG2a κ FGF-3 antibody, cited in 11 publications, provided at 200 µg/ml
- raised against an int-2 synthetic peptide of mouse origin
- FGF-3 Antibody (MSD 1) is recommended for detection of precursor and mature FGF-3 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-FGF-3 Antibody (MSD 1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FGF-3 Antibody (MSD 1) for WB and IHC(P) applications. These reagents are now offered in bundles with FGF-3 Antibody (MSD 1) (see ordering information below).
FGF-3 Antibody (MSD 1) is a mouse monoclonal IgG2a kappa light chain antibody that detects FGF-3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. FGF-3 Antibody (MSD 1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FGF-3 plays a crucial role in embryonic development and tissue repair, primarily functioning as a signaling molecule that promotes cell proliferation and differentiation. FGF-3 is particularly important in the development of the central nervous system and the formation of various tissues, including the skin and limbs. Proper regulation of FGF-3 is essential, as dysregulation can lead to developmental disorders and contribute to the progression of certain cancers. Understanding FGF-3 interactions with other fibroblast growth factors, such as FGF-1 and FGF-2, is vital for elucidating its role in cellular signaling pathways and therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FGF-3 Antibody (MSD 1) References:
- Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. | Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
- Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors. | Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
- Recent developments in the cell biology of basic fibroblast growth factor. | Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
- Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. | Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
- An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family. | Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
- Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus. | Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
- The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors. | Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
- Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. | Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
- Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression. | Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGF-3 Antibody (MSD 1) | sc-135 | 200 µg/ml | $322.00 | |||
FGF-3 Antibody (MSD 1): m-IgG Fc BP-HRP Bundle | sc-552977 | 200 µg Ab; 10 µg BP | $361.00 | |||
FGF-3 Antibody (MSD 1): m-IgGκ BP-HRP Bundle | sc-552976 | 200 µg Ab; 40 µg BP | $361.00 | |||
FGF-3 Antibody (MSD 1) AC | sc-135 AC | 500 µg/ml, 25% agarose | $424.00 | |||
FGF-3 Antibody (MSD 1) HRP | sc-135 HRP | 200 µg/ml | $322.00 | |||
FGF-3 Antibody (MSD 1) FITC | sc-135 FITC | 200 µg/ml | $336.00 | |||
FGF-3 Antibody (MSD 1) PE | sc-135 PE | 200 µg/ml | $349.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 488 | sc-135 AF488 | 200 µg/ml | $364.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 546 | sc-135 AF546 | 200 µg/ml | $364.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 594 | sc-135 AF594 | 200 µg/ml | $364.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 647 | sc-135 AF647 | 200 µg/ml | $364.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 680 | sc-135 AF680 | 200 µg/ml | $364.00 | |||
FGF-3 Antibody (MSD 1) Alexa Fluor® 790 | sc-135 AF790 | 200 µg/ml | $364.00 |