Date published: 2025-9-9

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CD206/Mannose Receptor/MMR 항체 (15-2): sc-58986

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데이터 시트
  • CD206/Mannose Receptor/MMR 항체(15-2) 는 마우스 monoclonal IgG1κ, 79간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • 유전자침묵제품은 비영리적인용도나 연구에만 사용가능합니다 자세한 정보보기.
  • 안티-CD206/Mannose Receptor/MMR 항체 (15-2)는 WB, IP, IF and FCM으로 mouse, rat and human유래의 CD206 를 감지하는 데에 추천한다.
  • 항-CD206/Mannose Receptor/MMR 항체(15-2)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • CD206/Mannose Receptor/MMR (15-2): sc-58986무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP 는 CD206/Mannose Receptor/MMR 항체 (15-2) for WB applications. 이 시약은 이제 CD206/Mannose Receptor/MMR 항체 (15-2)와 함께 번들로 제공됩니다(아래 주문 정보 참조).

빠른 링크

더보기

CD206/만노스 수용체/MMR 항체 (15-2)는 WB, IP, IF 및 FCM에 의해 마우스, 랫트 및 인간 기원의 CD206을 검출하는 IgG1 κ 마우스 단일 클론 CD206 항체 (또한 MRC1 항체로 지정됨)이다. CD206/만노스 수용체/MMR 항체 (15-2)는 비 conjug 항-CD206 항체 형태뿐만 아니라 아가로오스, HRP, PE, FITC 및 다중 Alexa Fluor® 접합체를 포함한 다중 접합 형태의 항-CD206 항체로 사용할 수 있다. 대식세포 만노스 수용체 유형 C (MMR 또는 MRC1)로도 알려져 있는 CD206은 유형 I 막 수용체 단백질이다. 이는 표적 분자에서 탄수화물 리간드를 인식할 수 있는 식세포 및 세포내피 수용체이다. 단백질의 세포외 부분은 8개의 C형 탄수화물 인식 도메인(CRD)을 포함하며, 이들은 함께 군집되어 당류에 대한 더 높은 친화력을 달성한다. CD206은 대식세포와 간 내피 세포에서 발견되며, 다중 C형 CRD를 포함하는 C형 렉틴의 유일하게 알려진 예이다. CD206은 대식세포에 의한 당단백질의 세포내이입을 매개하고 잠재적인 병원성 바이러스, 곰팡이 및 박테리아 표면의 고만노스 구조에 결합하여 식세포 삼킴으로써 중화된다. 염증 동안, CD206은 여러 만노스 함유 혈청 당단백질의 신속한 제거에 중요하지만 염증의 개시를 조절하지는 않는다. CD206은 주로 성숙한 조직의 대식세포 및 미성숙 수지상 세포뿐만 아니라 간 및 림프 내피 세포, 망막 돼지 상피 (RPE) 및 망상 세포에서 발현된다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

CD206/Mannose Receptor/MMR 항체 (15-2)

sc-58986
200 µg/ml
$316.00

CD206/Mannose Receptor/MMR (15-2): m-IgG Fc BP-HRP 번들

sc-526922
200 µg Ab; 10 µg BP
$354.00

CD206/Mannose Receptor/MMR (15-2): m-IgG1 BP-HRP 번들

sc-532295
200 µg Ab; 20 µg BP
$354.00

CD206/Mannose Receptor/MMR 항체 (15-2) AC

sc-58986 AC
500 µg/ml, 25% agarose
$416.00

CD206/Mannose Receptor/MMR 항체 (15-2) HRP

sc-58986 HRP
200 µg/ml
$316.00

CD206/Mannose Receptor/MMR 항체 (15-2) FITC

sc-58986 FITC
200 µg/ml
$330.00

CD206/Mannose Receptor/MMR 항체 (15-2) PE

sc-58986 PE
200 µg/ml
$343.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 488

sc-58986 AF488
200 µg/ml
$357.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 546

sc-58986 AF546
200 µg/ml
$357.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 594

sc-58986 AF594
200 µg/ml
$357.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 647

sc-58986 AF647
200 µg/ml
$357.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 680

sc-58986 AF680
200 µg/ml
$357.00

CD206/Mannose Receptor/MMR 항체 (15-2) Alexa Fluor® 790

sc-58986 AF790
200 µg/ml
$357.00

What is the recommended starting dilution for IHC for sc-58986: CD206 (15-2) monoclonal antibody?

Asked by: zxcvbbnm
Thank you for your question.This antibody can be used for frozen samples and paraffin section is not currently a recommended application. The specific dilution:immunofluorescence or immunohistochemistry is starting dilution 1:50, dilution range 1:50-1:500.If you have any further questions, please call us toll-free at (800) 457-3801 option 2, e-mail <scbt@scbt.com>, or use the live chat on our website. Thank you.
Answered by: Jiajun Z
Date published: 2022-11-07

Can this antibody functionally block mannose binding?

Asked by: hwash
Thank you for your question. Anti-CD206/Mannose Receptor/MMR Antibody (15-2) is intended and recommended for detection of CD206 of mouse, rat and human origin by WB, IP, IF and FCM. It has not been tested for its blocking properties and we do not have any data to support such an assay.
Answered by: Tech Support Europe
Date published: 2022-09-05

您好,想做大鼠石蜡切片的免疫荧光双标, CD206 Antibody (D-1): sc-376108 and CD206 Antibody (15-2): sc-58986 两个抗体都能用吗,哪个更合适呢?

Asked by: xiaoyounvzi
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2023-10-15

您好!请问CD206抗体(SC-58986)是否可以用于M2型小胶质细胞的免疫组化和免疫荧光染色?

Asked by: PURPLE
感谢您的提问。请发邮件至asia@scbio.cn,联系我们的技术服务部门。 Thank you for your question. Please contact our Technical Service Department at asia@scbio.cn.
Answered by: Technical Support 12
Date published: 2021-07-07

Can this Ab (sc-58986: CD206 (15-2)) is good for IP? What will be the recommended dilution for IP?

Asked by: Apricano
Thank you for your question. Anti-CD206 Antibody (15-2) is recommended for detection of CD206 of mouse, rat and human origin by WB, IP, IF and FCM. For IP we recommend 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) You can find our recommended protocol for IP under this link: https://www.scbt.com/resources/protocols/immunoprecipitation-western-blots
Answered by: Tech Support Europe
Date published: 2020-12-08

Can I use sc-58986 for indirect flow cytometry in mouse and rat? If I can, do you have a recommended fluorescent secondary antibody?

Asked by: ykwq
Thank you for your question. This antibody is recommended for flow cytometry (FCM) in mouse, rat and human samples. We have not specifically tested this antibody in indirect flow cytometry, but if you want to try it we would recommend using anti-mouse IgG1 for detection. One example would be our m-IgGκ BP-CFL 488: sc-516176.
Answered by: Technical Support
Date published: 2019-04-13

Can I use it to do Immunofluorescence double staining?My sample is from Mouse Ovary and Endometrium Tissue and I am afraid it can not be stained well.

Asked by: Puff Daddy
Thank you for your question. Yes, this antibody is mouse reactive and should be fine for double straining on mouse samples.
Answered by: Technical Support
Date published: 2019-01-05

Hi, do you have the CD206 antibody (15-2) conjugated to AF 647 for flow cytometry? 

Asked by: Varsha
Thank you for your question. Yes, we offer this antibody conjugated to AlexaFluor 647. The catalog number is: sc-58986 AF647.
Answered by: Tech Service
Date published: 2017-12-06
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Rated 5 out of 5 by from Good antibodyThis antibody worked very well with fixed frozen mouse tissue sections for IF
Date published: 2018-10-03
Rated 3 out of 5 by from not clear bandwe used this sample to do the western blot ,the sample is the Mouse monoclonal antibody .we used this sample to dectect the CD206 of RAW246.7 cell.we detected that there are no bands at approximately 170 kDa .
Date published: 2017-11-20
Rated 4 out of 5 by from clear bandwe used this sample to do the western blot ,the sample is the Mouse monoclonal antibody .we used this sample to dectect the B7-2 of RAW246.7 cell.we detected that the band of B7-2 was approximately 66 kDa .
Date published: 2017-10-12
Rated 4 out of 5 by from Positive results in western blot analysisPositive results in western blot analysis of CD206 expression in human liver tissue extract. -SCBT QC
Date published: 2015-03-08
Rated 4 out of 5 by from SingleSingle, strong band in western blot analysis of CD206 expression in human liver tissue extract. -SCBT QC
Date published: 2015-02-12
Rated 4 out of 5 by from Clean IF staining in human THPClean IF staining in human THP-1 cells. -SCBT Publication Review
Date published: 2015-01-26
Rated 4 out of 5 by from Published WB/IF using human cultured PBMCsPublished WB/IF using human cultured PBMCs. -SCBT Publication Review
Date published: 2013-08-08
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CD206/Mannose Receptor/MMR 항체 (15-2) is rated 4.0 out of 5 by 7.
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