ADH Inhibitors for functional analysis of cellular responses to ADH
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ADH4 (alcohol dehydrogenase 4) is a 380 amino acid protein that belongs to the zinc-containing alcohol dehydrogenase family of enzymes that function to metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and existing as a homodimer, ADH4 uses zinc as a cofactor to catalyze the NAD+-dependent conversion of an alcohol to an aldehyde or a ketone, thereby participating in the metabolic degradation of alcohols within the body. Multiple isoforms of ADH4 exist due to alternative splicing events. The gene encoding ADH4 maps to a cluster of alcohol dehydrogenase genes on human chromosome 4, a chromosome that encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-134249: ADH4 (NB-B2) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Germaine
Thank you for your question. Yes, sc-134249: ADH4 (NB-B2) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: