P2X1 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BzATP triethylammonium salt | 112898-15-4 | sc-203862 | 5 mg | $156.00 | 4 | |
BzATP triethylammonium salt is a potent agonist of P2X1 receptors, known for its ability to induce rapid ion channel activation. Its unique triethylammonium moiety enhances solubility and receptor affinity, facilitating swift interactions with the binding site. This compound triggers a pronounced influx of cations, particularly calcium, leading to significant alterations in cellular signaling dynamics. The kinetics of its action are characterized by a quick onset and a brief duration, underscoring its role in modulating purinergic responses. | ||||||
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
ATP directly enhances P2X1 activity by acting as its primary agonist. ATP binding leads to the opening of the P2X1 ion channel, facilitating cation influx, crucial for P2X1's role in neurotransmission and muscle contraction. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
NF449, while known as a P2X1 antagonist, can indirectly enhance P2X1 activity through receptor desensitization followed by a rebound increase in receptor sensitivity or upregulation. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin, a P2X1 receptor antagonist, can enhance P2X1 activity indirectly through receptor desensitization and subsequent upregulation or increased receptor responsiveness. | ||||||
Victoria Blue B | 2580-56-5 | sc-216055 sc-216055A | 25 g 100 g | $37.00 $124.00 | 1 | |
Reactive Blue 2, known to inhibit P2X1, may indirectly increase P2X1 activity over time by inducing receptor desensitization and compensatory mechanisms leading to receptor upregulation. | ||||||
Probenecid | 57-66-9 | sc-202773 sc-202773A sc-202773B sc-202773C | 1 g 5 g 25 g 100 g | $28.00 $39.00 $100.00 $277.00 | 28 | |
Probenecid, often used to inhibit organic anion transporters, can indirectly enhance P2X1 activity by modulating extracellular ATP levels, thus potentially influencing P2X1 receptor activation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc can enhance P2X1 receptor activity by acting as a modulatory agent. It may bind to distinct sites on the receptor, influencing its conformation and responsiveness to ATP. | ||||||