Date published: 2026-4-27

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cathepsin B Substrates

Santa Cruz Biotechnology now offers a broad range of cathepsin B Substrates for use in various applications. Cathepsin B substrates are crucial tools in the study of cathepsin B, a lysosomal cysteine protease that plays a vital role in intracellular protein degradation, apoptosis, and various aspects of cellular homeostasis. This enzyme is involved in the breakdown of proteins within the lysosome, a process essential for the recycling of cellular components and the regulation of cellular metabolism. In scientific research, cathepsin B is often studied for its role in pathological conditions such as cancer, where it contributes to tumor invasion and metastasis, as well as in neurodegenerative diseases, where its dysregulation can lead to cell death. By using cathepsin B substrates, researchers can specifically monitor the activity of this enzyme, allowing for detailed investigations into its function under normal and disease conditions. These substrates are particularly valuable in high-throughput screening assays aimed at identifying inhibitors or activators of cathepsin B, thereby facilitating the study of the enzyme's role in various biological processes. The ability to measure cathepsin B activity with precision provides insights into the mechanisms by which this protease contributes to cellular function and how its activity is regulated. Additionally, cathepsin B substrates are used in studies exploring the enzyme's role in the immune response, where it is involved in antigen processing and presentation. The use of these substrates is essential for advancing research in fields ranging from cell biology to oncology and immunology. View detailed information on our available cathepsin B Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cathepsin L substrate Substrate

65147-22-0sc-3136A
sc-3136
sc-3136B
5 mg
25 mg
100 mg
$102.00
$265.00
$708.00
11
(0)

Cathepsin L substrate is a specialized peptide that exhibits unique interactions with cathepsin L, facilitating substrate recognition and cleavage. Its structure includes specific amino acid sequences that enhance binding affinity, promoting efficient proteolytic activity. The substrate's conformation allows for optimal positioning within the enzyme's active site, influencing reaction kinetics and substrate turnover. This specificity can lead to distinct cellular signaling pathways, highlighting its role in proteolytic regulation.

Nα-Benzoyl-L-arginine 4-methoxy-β-naphthylamide hydrochloride

100900-33-2sc-215529
sc-215529A
sc-215529B
25 mg
50 mg
250 mg
$218.00
$312.00
$520.00
1
(0)

Nα-Benzoyl-L-arginine 4-methoxy-β-naphthylamide hydrochloride serves as a selective inhibitor of cathepsin B, characterized by its ability to form stable interactions with the enzyme's active site. The compound's unique aromatic and aliphatic moieties enhance hydrophobic interactions, promoting a tight binding affinity. This specificity alters the enzyme's catalytic efficiency, impacting proteolytic pathways and influencing cellular homeostasis through modulation of protein degradation processes.