p35 Antibody (G-7): sc-518015
- p35 Antibody (G-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 69-140 mapping near the N-terminus of p35 of human origin
- recommended for detection of p35 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p35 Antibody (G-7) for WB applications. These reagents are now offered in bundles with p35 Antibody (G-7) (see ordering information below).
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SEE ALSO...
p35 Antibody (G-7) is a mouse monoclonal IgG2a antibody that detects p35 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p35 plays a crucial role as a regulatory subunit of cyclin-dependent kinase-5 (Cdk5), which is essential for various neuronal functions, including neuronal development, synaptic plasticity, and the regulation of the cell cycle in post-mitotic neurons. p35 (G-7) antibody enables researchers to study p35′s ability to activate Cdk5, thereby influencing the kinase′s activity and downstream signaling pathways. p35 is expressed predominantly in the brain, where p35 forms a complex with Cdk5, facilitating enzymatic function. In contrast, a truncated form of p35, known as p25, is found in various tissues and can lead to aberrant Cdk5 activity, which has been implicated in neurodegenerative diseases. anti-p35 antibody (G-7) serves as a valuable tool for studying the dynamics of Cdk5 regulation and implications in neuronal health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p35 Antibody (G-7) | sc-518015 | 200 µg/ml | $322.00 | |||
p35 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-538846 | 200 µg Ab; 10 µg BP | $361.00 | |||
p35 Antibody (G-7): m-IgGκ BP-HRP Bundle | sc-536530 | 200 µg Ab; 40 µg BP | $361.00 | |||
p35 Antibody (G-7): m-IgG2a BP-HRP Bundle | sc-548426 | 200 µg Ab; 10 µg BP | $361.00 |