NRAMP 1 Antibody (D-9): sc-398036
- NRAMP 1 Antibody (D-9) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 71-98 within an internal region of NRAMP 1 of human origin
- recommended for detection of NRAMP 1 and NRAMP 2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NRAMP 1 Antibody (D-9) for WB applications. These reagents are now offered in bundles with NRAMP 1 Antibody (D-9) (see ordering information below).
QUICK LINKS
NRAMP 1 Antibody (D-9) is a mouse monoclonal IgG2b antibody that detects NRAMP 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NRAMP 1 is an essential intracellular macrophage protein located at the phagosomal membrane, where NRAMP 1 plays a critical role as a divalent cation transporter for iron (Fe2+), zinc (Zn2+), and manganese (Mn2+). NRAMP 1 functions as a pH-dependent antiporter, facilitating the transport of metal ions into or out of the phagosome against a proton gradient, which is vital for maintaining metal ion homeostasis within immune cells. Proper functioning of NRAMP 1 is particularly important in the context of immune response, as polymorphisms in the NRAMP 1 gene have been associated with increased susceptibility to infections such as Mycobacterium tuberculosis and leprosy in humans. NRAMP 1′s role in metal ion transport underscores NRAMP 1′s significance in various physiological processes, including cellular signaling and the regulation of oxidative stress. With broad species reactivity and versatility in multiple applications, anti-NRAMP 1 antibody (D-9) serves as an invaluable tool for researchers studying immune function and metal ion transport mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NRAMP 1 Antibody (D-9) | sc-398036 | 200 µg/ml | $322.00 | |||
NRAMP 1 Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-538357 | 200 µg Ab; 10 µg BP | $361.00 | |||
NRAMP 1 Antibody (D-9): m-IgGκ BP-HRP Bundle | sc-535952 | 200 µg Ab; 40 µg BP | $361.00 | |||
NRAMP 1 Antibody (D-9): m-IgG2b BP-HRP Bundle | sc-549945 | 200 µg Ab; 10 µg BP | $361.00 | |||
NRAMP 1 (D-9) Neutralizing Peptide | sc-398036 P | 100 µg/0.5 ml | $69.00 |