NFATc4 Antibody (F-4): sc-515584
- NFATc4 Antibody (F-4) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 877-902 at the C-terminus of NFATc4 of human origin
- recommended for detection of NFATc4 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-515584 X, 200 µg/0.1 ml)
- See NFATc4 (B-2): sc-271597 for NFATc4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for NFATc4 Antibody (F-4) for WB applications. This reagent is now offered in a bundle with NFATc4 Antibody (F-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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NFATc4 Antibody (F-4) is a mouse monoclonal IgM antibody that detects NFATc4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NFATc4, or nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4, is a crucial component of the nuclear factors of activated T cells DNA-binding transcription complex, which plays a significant role in regulating cytokine gene expression, cardiac hypertrophy, and adipocyte differentiation. NFATc4 is primarily located in the cytoplasm and translocates to the nucleus upon T cell receptor stimulation, where NFATc4 influences the transcription of key cytokines, including interleukin-2 and interleukin-4. Proper functioning of NFATc4 is vital for T cell activation and immune response, as NFATc4 dysregulation can lead to various immunological disorders. Additionally, NFATc4 undergoes post-translational modifications, such as phosphorylation by p38 MAP kinase, which modulates NFATc4 activity and stability, further underscoring NFATc4′s importance in cellular signaling pathways. Anti-NFATc4 antibody (F-4) is an essential tool for researchers studying T cell biology and related immunological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NFATc4 Antibody (F-4) | sc-515584 | 200 µg/ml | $322.00 | |||
NFATc4 Antibody (F-4): m-IgGκ BP-HRP Bundle | sc-552187 | 200 µg Ab; 40 µg BP | $361.00 | |||
NFATc4 (F-4) Neutralizing Peptide | sc-515584 P | 100 µg/0.5 ml | $69.00 | |||
NFATc4 Antibody (F-4) X | sc-515584 X | 200 µg/0.1 ml | $322.00 |