KLHDC4 Antibody (E-4): sc-515459

KLHDC4 Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects KLHDC4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KLHDC4, or kelch domain-containing protein 4, is a 520 amino acid protein characterized by the presence of six kelch repeats and exists in three alternatively spliced isoforms, which may play distinct roles in cellular processes. KLHDC4 is primarily located in the cytoplasm, where KLHDC4 is believed to be involved in various cellular functions, including the regulation of protein stability and the modulation of signaling pathways. Proper localization of KLHDC4 is crucial, as KLHDC4 may interact with other proteins to influence cellular responses to stress and maintain homeostasis. Dysregulation of KLHDC4 has been implicated in several diseases, highlighting KLHDC4′s potential as a biomarker for pathological conditions. The gene encoding KLHDC4 is situated on human chromosome 16q24.2, a region associated with various genetic disorders, including Crohn′s disease and Rubinstein-Taybi syndrome, underscoring KLHDC4′s importance in both health and disease. With versatile applications and significant biological relevance, anti-KLHDC4 antibody (E-4) serves as an essential tool for researchers investigating KLHDC4′s role in human health and disease.

The preferred KLHDC4 antibody is KLHDC4 Antibody (H-9): sc-398467.