m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for IFITM1/2/3 Antibody (F-12) for WB and IHC(P) applications. This reagent is now offered in a bundle with IFITM1/2/3 Antibody (F-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
IFITM1/2/3 Antibody (F-12) is a high quality monoclonal IFITM1/2/3 antibody (also designated IFITM1 antibody, IFITM2 antibody, IFITM3 antibody, IFM1 antibody antibody, pan-Interferon Induced Transmembrane Protein antibody, Interferon Induced Transmembrane Protein antibody, Interferon-Induced Transmembrane Protein 1/2/3 antibody, CD225 antibody, pan-IFITM antibody, DSPA2a antibody, DSPA2b antibody, or DSPA2c antibody) suitable for the detection of the IFITM1/2/3 protein of human origin. IFITM1/2/3 Antibody (F-12) is available as both the non-conjugated anti-IFITM1/2/3 antibody form, as well as multiple conjugated forms of anti-IFITM1/2/3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and Fragilis (also known as Ifitm3) demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences