m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for HSP 27 Antibody (F-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with HSP 27 Antibody (F-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
HSP 27 Antibody (F-4) is a high quality monoclonal HSP 27 antibody (also designated HSPB1 antibody, heat shock protein family B (small) member 1 antibody, HSP27 antibody) suitable for the detection of the HSP27 (HSPB1) protein of mouse, rat and human origin. HSP 27 Antibody (F-4) is available as both the non-conjugated anti-HSP 27 antibody form, as well as multiple conjugated forms of anti-HSP 27 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent poly-peptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The low molecular weight family includes HSP 10, HSP 20, HSP 27, HSP 32 and HSP 40. HSP 27 is a constitutively expressed cytoplasmic protein that co-localizes to the nucleus upon stress induced by insult. Heat, cytokines and hormones are among the factors that stimulate the synthesis of HSP 27. In vitro, HSP 27 becomes highly phosphorylated following exposure to stress. The discovery that HSP 27 is regulated by hormones such as estrogen has led to studies establishing a relationship between HSP 27 and breast cancer.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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