cathepsin L Antibody (B-8): sc-393770

cathepsin L Antibody (B-8) is a mouse monoclonal IgG2a kappa light chain antibody engineered to recognize an epitope mapping between amino acids 306-334 at the C-terminus of cathepsin L, also known as CTSL, major excreted protein (MEP), or CATL. anti-cathepsin L antibody (B-8) demonstrates strong reactivity with cathepsin L from both mouse and rat species, making anti-cathepsin L antibody (B-8) ideal for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cathepsin L is a vital lysosomal cysteine protease responsible for the intracellular degradation of key proteins including collagen, elastin, and α-1 protease inhibitor, which are essential for maintaining cellular metabolism and homeostasis. The functional importance of cathepsin L lies in its role in processes such as tissue remodeling, immune responses, and the progression of various diseases including cancer, arthritis, and cardiovascular disorders. By accurately degrading extracellular matrix components, cathepsin L facilitates cell migration and invasion, which are critical in both normal physiological and pathological conditions. Additionally, cathepsin L is involved in the processing of antigenic peptides, thereby playing a significant role in the immune system′s ability to recognize and respond to pathogens. cathepsin L monoclonal antibody (B-8) enables researchers to precisely monitor and study the expression, regulation, and functional dynamics of cathepsin L, providing valuable insights into its involvement in disease mechanisms and potential as a therapeutic target. Whether you are investigating protein degradation pathways, exploring cellular metabolism, or examining the intricate roles of proteases in disease, anti-cathepsin L antibody (B-8) offers the specificity and reliability necessary to advance your scientific research and discoveries.

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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.

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The preferred cathepsin L antibody is cathepsin L Antibody (33/2): sc-32320.