Date published: 2025-9-12

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LOC439950 アクチベーター

The term LOC439950 Activators refers to a class of chemical agents that specifically interact with and increase the activity of the protein product of the gene designated as LOC439950. This alphanumeric label indicates a locus or a specific position within the human genome that has been identified but whose gene product and associated functions may not be fully characterized. The 'LOC' prefix is commonly assigned to loci that are thought to represent putative protein-coding regions within the genome, and the succeeding number serves as a unique identifier for researchers to reference this specific genomic segment. Activators in this context are molecules that enhance the biological activity of the protein encoded by LOC439950. They may do so through various mechanisms, such as increasing the transcriptional rates of the gene, stabilizing the protein product to prolong its cellular lifespan, or facilitating its interactions with other proteins or biochemical pathways within the cell.

The discovery and development of LOC439950 activators would involve a multi-disciplinary approach, initially focusing on the characterization of the LOC439950 protein. If the protein's structure could be resolved through methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron microscopy, this would provide invaluable insights into potential binding sites for small molecule activators. These activators would be designed to bind to the protein with high specificity, thereby enhancing its natural activity without disrupting other cellular mechanisms. Subsequent steps would include the synthesis of a diverse chemical library, with each compound designed to interact with the identified binding sites on the LOC439950 protein. Sophisticated high-throughput screening techniques would then be employed to test these compounds for their ability to modulate the protein's activity. Hits from this screening would be subjected to an iterative process of chemical modification to fine-tune their properties, such as binding affinity, specificity, and the ability to positively modulate the LOC439950 protein's activity. Through this cycle of design, testing, and refinement, effective LOC439950 activators would be developed, each uniquely crafted to engage with the protein product of the LOC439950 gene and elevate its functional state within the cellular context.

関連項目

Items 1 to 10 of 12 total

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製品名CAS #カタログ #数量価格引用文献レーティング

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Wntシグナル伝達経路に影響を与え、遺伝子転写を変化させ、アンチセンスRNAを含むncRNAのレベルに影響を与える可能性がある。

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

DNAメチル化酵素阻害剤で、DNAの脱メチル化を引き起こし、特定のノンコーディングRNAの転写を活性化する可能性がある。

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

DNAを脱メチル化し、ncRNAの転写を促進する可能性のある非ヌクレオシドDNAメチル化酵素阻害剤。

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

ヒストン脱アセチル化酵素阻害剤で、クロマチン構造を変化させ、アンチセンス転写物を含むncRNAの発現を増加させる可能性がある。

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

植物由来の化合物で、多くのシグナル伝達経路を調節し、エピジェネティック効果によりncRNAの発現に影響を与える可能性がある。

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

遺伝子の発現に広く影響を与えることが示されており、おそらくエピジェネティックな調節能力によりncRNAの転写に影響を与える。

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
18
(3)

ヒストン脱アセチル化酵素阻害剤として、クロマチン動態を変化させ、ncRNAの発現に影響を与える可能性がある。

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

アブラナ科の野菜に含まれる化合物で、遺伝子発現に影響を与え、エピジェネティックなメカニズムを通じてncRNAレベルに影響を与える可能性がある。

(±)-Methyl Jasmonate

39924-52-2sc-205386
sc-205386A
sc-205386B
sc-205386C
sc-205386D
sc-205386E
sc-205386F
1 g
5 g
10 g
50 g
100 g
500 g
1 kg
$35.00
$103.00
$200.00
$873.00
$1638.00
$6942.00
$12246.00
(1)

植物ホルモンは、アンチセンスRNAの転写を含む幅広い遺伝子発現パターンに影響を与える可能性がある。

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

もう一つのDNAメチル化酵素阻害剤は、DNAのメチル化を低下させ、ncRNAの転写に影響を与える可能性がある。