Date published: 2026-7-10

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GPx Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GPx Antibodies for research in oxidative stress and cellular defense mechanisms. GPx Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Glutathione peroxidases (GPx) play a crucial role in protecting cells from oxidative damage by catalyzing the reduction of hydrogen peroxide and organic peroxides, thereby maintaining cellular redox balance. GPx importance extends to various physiological processes, including inflammation, apoptosis, and cellular signaling. Dysregulation of GPx activity has been implicated in numerous diseases, making research in this area particularly significant. GPx monoclonal antibodies enable precise detection and analysis of oxidative stress markers in biological samples. Researchers can utilize GPx monoclonal antibodies to explore cellular responses to oxidative stress and investigate potential therapeutic interventions. Understanding GPx function and regulation contributes to the development of new treatment strategies for oxidative stress-related conditions. Santa Cruz Biotechnology monoclonal antibodies for GPx research support scientists worldwide in advancing our understanding of oxidative stress and its impact on human health.

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GPx Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Glutathione Peroxidase 1/2/GPX1/2 Antibody (B-6)

sc-133160mouse IgG1 κ50-201 (h)WB, IP, IF, IHC(P), ELISAm, r, h
83
(13)

Glutathione Peroxidase 1/2/GPX1/2 Antibody (D-12)

sc-133152mouse IgG1 κ50-201 (h)WB, IP, IF, IHC(P), ELISAm, r, h
19
(3)

Glutathione Peroxidase 1/2/GPX1/2 Antibody (E-7)

sc-74498mouse IgG2b κ50-201 (h)WB, IP, IF, ELISAm, r, h
8
(2)

Glutathione Peroxidase 4/GPX4 Antibody (E-12)

sc-166570mouse IgG2b κ108-197 (h)WB, IP, IF, IHC(P), ELISAm, r, h
84
(22)

Glutathione Peroxidase 4/GPX4 Antibody (B-12)

sc-166120mouse IgG1 κ108-197 (h)WB, IP, IF, ELISAm, r, h
18
(5)

Glutathione Peroxidase 4/GPX4 Antibody (D-3)

sc-166437mouse IgG2a κ108-197 (h)WB, IP, IF, ELISAm, r, h
2
(1)

Glutathione Peroxidase 5/GPX5 Antibody (D-3)

sc-390092mouse IgG2b κ22-66 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(1)

Glutathione Peroxidase 5/GPX5 Antibody (D-2)

sc-376877mouse IgG2a κ22-61 (m)WB, IP, IF, ELISAm, r
2
(1)

Glutathione Peroxidase 5/GPX5 Antibody (G-1)

sc-390093mouse IgG2a κ22-66 (h)WB, IP, IF, ELISAm, r, h
1
(1)

GPx siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Glutathione Peroxidase 1/GPX1 siRNA (h)

sc-40646hGene SilencingN/A
3
(0)

Glutathione Peroxidase 1/GPX1 shRNA Plasmid (h)

sc-40646-SHhGene SilencingPuromycin
3
(0)

Glutathione Peroxidase 1/GPX1 shRNA (h) Lentiviral Particles

sc-40646-VhGene SilencingPuromycin
3
(0)

Glutathione Peroxidase 1/GPX1 siRNA (m)

sc-40647mGene SilencingN/A
1
(0)

Glutathione Peroxidase 1/GPX1 shRNA Plasmid (m)

sc-40647-SHmGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 1/GPX1 shRNA (m) Lentiviral Particles

sc-40647-VmGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 2/GPX2 siRNA (h)

sc-62415hGene SilencingN/A
2
(0)

Glutathione Peroxidase 2/GPX2 shRNA Plasmid (h)

sc-62415-SHhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 2/GPX2 shRNA (h) Lentiviral Particles

sc-62415-VhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 2/GPX2 siRNA (m)

sc-62416mGene SilencingN/A0
(0)

Glutathione Peroxidase 2/GPX2 shRNA Plasmid (m)

sc-62416-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 2/GPX2 shRNA (m) Lentiviral Particles

sc-62416-VmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 3/GPX3 siRNA (h)

sc-62417hGene SilencingN/A
1
(0)

Glutathione Peroxidase 3/GPX3 shRNA Plasmid (h)

sc-62417-SHhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 3/GPX3 shRNA (h) Lentiviral Particles

sc-62417-VhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 3/GPX3 siRNA (m)

sc-62418mGene SilencingN/A0
(0)

Glutathione Peroxidase 3/GPX3 shRNA Plasmid (m)

sc-62418-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 3/GPX3 shRNA (m) Lentiviral Particles

sc-62418-VmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 4/GPX4 siRNA (h)

sc-44465hGene SilencingN/A
2
(0)

Glutathione Peroxidase 4/GPX4 shRNA Plasmid (h)

sc-44465-SHhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 4/GPX4 shRNA (h) Lentiviral Particles

sc-44465-VhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 4/GPX4 siRNA (m)

sc-63302mGene SilencingN/A
1
(0)

Glutathione Peroxidase 4/GPX4 shRNA Plasmid (m)

sc-63302-SHmGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 shRNA (m) Lentiviral Particles

sc-63302-VmGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 5/GPX5 siRNA (h)

sc-62419hGene SilencingN/A
1
(0)

Glutathione Peroxidase 5/GPX5 shRNA Plasmid (h)

sc-62419-SHhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 5/GPX5 shRNA (h) Lentiviral Particles

sc-62419-VhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 5/GPX5 siRNA (m)

sc-62420mGene SilencingN/A0
(0)

Glutathione Peroxidase 5/GPX5 shRNA Plasmid (m)

sc-62420-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 5/GPX5 shRNA (m) Lentiviral Particles

sc-62420-VmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 6/GPX6 siRNA (h)

sc-62421hGene SilencingN/A0
(0)

Glutathione Peroxidase 6/GPX6 shRNA Plasmid (h)

sc-62421-SHhGene SilencingPuromycin0
(0)

Glutathione Peroxidase 6/GPX6 shRNA (h) Lentiviral Particles

sc-62421-VhGene SilencingPuromycin0
(0)

Glutathione Peroxidase 6/GPX6 siRNA (m)

sc-62422mGene SilencingN/A0
(0)

Glutathione Peroxidase 6/GPX6 shRNA Plasmid (m)

sc-62422-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 6/GPX6 shRNA (m) Lentiviral Particles

sc-62422-VmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 7/GPX7 siRNA (h)

sc-78832hGene SilencingN/A
1
(0)

Glutathione Peroxidase 7/GPX7 shRNA Plasmid (h)

sc-78832-SHhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 7/GPX7 shRNA (h) Lentiviral Particles

sc-78832-VhGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 7/GPX7 siRNA (m)

sc-145747mGene SilencingN/A0
(0)

Glutathione Peroxidase 7/GPX7 shRNA Plasmid (m)

sc-145747-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 7/GPX7 shRNA (m) Lentiviral Particles

sc-145747-VmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 8/GPX8 siRNA (h)

sc-91950hGene SilencingN/A0
(0)

Glutathione Peroxidase 8/GPX8 shRNA Plasmid (h)

sc-91950-SHhGene SilencingPuromycin0
(0)

Glutathione Peroxidase 8/GPX8 shRNA (h) Lentiviral Particles

sc-91950-VhGene SilencingPuromycin0
(0)

Glutathione Peroxidase 8/GPX8 siRNA (m)

sc-108669mGene SilencingN/A0
(0)

Glutathione Peroxidase 8/GPX8 shRNA Plasmid (m)

sc-108669-SHmGene SilencingPuromycin0
(0)

Glutathione Peroxidase 8/GPX8 shRNA (m) Lentiviral Particles

sc-108669-VmGene SilencingPuromycin0
(0)

GPx CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Glutathione Peroxidase 1/GPX1 CRISPR/Cas9 KO Plasmid (h)

sc-400631Gene Knockouth0
(0)

Glutathione Peroxidase 2/GPX2 CRISPR/Cas9 KO Plasmid (h)

sc-406827Gene Knockouth0
(0)

Glutathione Peroxidase 3/GPX3 CRISPR/Cas9 KO Plasmid (m)

sc-420664Gene Knockoutm0
(0)

Glutathione Peroxidase 4/GPX4 CRISPR/Cas9 KO Plasmid (h)

sc-401558Gene Knockouth0
(0)

Glutathione Peroxidase 4/GPX4 HDR Plasmid (h)

sc-401558-HDRHomology Directed Repairh0
(0)

Glutathione Peroxidase 4/GPX4 CRISPR/Cas9 KO Plasmid (m)

sc-436949Gene Knockoutm0
(0)

Glutathione Peroxidase 4/GPX4 HDR Plasmid (m)

sc-436949-HDRHomology Directed Repairm0
(0)

Glutathione Peroxidase 6/GPX6 CRISPR/Cas9 KO Plasmid (h)

sc-406587Gene Knockouth0
(0)

Glutathione Peroxidase 6/GPX6 HDR Plasmid (h)

sc-406587-HDRHomology Directed Repairh0
(0)

Glutathione Peroxidase 7/GPX7 CRISPR/Cas9 KO Plasmid (h)

sc-404694Gene Knockouth0
(0)

Glutathione Peroxidase 7/GPX7 HDR Plasmid (h)

sc-404694-HDRHomology Directed Repairh0
(0)

Glutathione Peroxidase 8/GPX8 CRISPR/Cas9 KO Plasmid (h)

sc-404847Gene Knockouth0
(0)

Glutathione Peroxidase 8/GPX8 HDR Plasmid (h)

sc-404847-HDRHomology Directed Repairh0
(0)

GPx CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Glutathione Peroxidase 1/GPX1 Double Nickase Plasmid (h)

sc-400631-NICGene Knockouth0
(0)

Glutathione Peroxidase 1/GPX1 Double Nickase Plasmid (h2)

sc-400631-NIC-2Gene Knockouth0
(0)

Glutathione Peroxidase 1/GPX1 Double Nickase Plasmid (m)

sc-420662-NICGene Knockoutm0
(0)

Glutathione Peroxidase 3/GPX3 Double Nickase Plasmid (h)

sc-402413-NICGene Knockouth0
(0)

Glutathione Peroxidase 3/GPX3 Double Nickase Plasmid (h2)

sc-402413-NIC-2Gene Knockouth0
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (h)

sc-401558-NICGene Knockouth0
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (h2)

sc-401558-NIC-2Gene Knockouth0
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (m)

sc-436949-NICGene Knockoutm0
(0)

Glutathione Peroxidase 5/GPX5 Double Nickase Plasmid (h)

sc-405279-NICGene Knockouth0
(0)

Glutathione Peroxidase 5/GPX5 Double Nickase Plasmid (h2)

sc-405279-NIC-2Gene Knockouth0
(0)

Glutathione Peroxidase 7/GPX7 Double Nickase Plasmid (h)

sc-404694-NICGene Knockouth0
(0)

Glutathione Peroxidase 7/GPX7 Double Nickase Plasmid (h2)

sc-404694-NIC-2Gene Knockouth0
(0)

GPx CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Glutathione Peroxidase 1/GPX1 CRISPR Activation Plasmid (h)

sc-400631-ACTGene Activationh0
(0)

Glutathione Peroxidase 1/GPX1 CRISPR Activation Plasmid (m)

sc-420662-ACTGene Activationm0
(0)

Glutathione Peroxidase 2/GPX2 CRISPR Activation Plasmid (h)

sc-406827-ACTGene Activationh0
(0)

Glutathione Peroxidase 2/GPX2 CRISPR Activation Plasmid (h2)

sc-406827-ACT-2Gene Activationh0
(0)

Glutathione Peroxidase 2/GPX2 CRISPR Activation Plasmid (m)

sc-420663-ACTGene Activationm0
(0)

Glutathione Peroxidase 3/GPX3 CRISPR Activation Plasmid (h)

sc-402413-ACTGene Activationh0
(0)

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (h)

sc-401558-ACTGene Activationh0
(0)

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (h2)

sc-401558-ACT-2Gene Activationh0
(0)

Glutathione Peroxidase 4/GPX4 Lentiviral Activation Particles (h)

sc-401558-LACGene Activationh0
(0)

Glutathione Peroxidase 5/GPX5 CRISPR Activation Plasmid (h)

sc-405279-ACTGene Activationh0
(0)

Glutathione Peroxidase 7/GPX7 CRISPR Activation Plasmid (h)

sc-404694-ACTGene Activationh0
(0)

Glutathione Peroxidase 7/GPX7 CRISPR Activation Plasmid (h2)

sc-404694-ACT-2Gene Activationh0
(0)

Glutathione Peroxidase 8/GPX8 CRISPR Activation Plasmid (h)

sc-404847-ACTGene Activationh0
(0)

Glutathione Peroxidase 8/GPX8 CRISPR Activation Plasmid (h2)

sc-404847-ACT-2Gene Activationh0
(0)