Anti-CUL-5 Antibody F-6 è un monoclonale di topo IgG1 κ CUL-5 antibody, citato in 11 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 1-300 mappati al N-terminus di CUL-5 (cullin-5) di origine human
CUL-5 Antibody (F-6) é raccomandato per il rilevamento di CUL-5 di origine mouse, rat e human in WB, IP, IF e ELISA; anche reattivo con ulteriori specie, incluse e equine, bovine and porcine
CUL-5 Antibody (F-6) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di CUL-5 (F-6): sc-373822.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CUL-5 Antibody (F-6) for WB applications. These reagents are now offered in bundles with CUL-5 Antibody (F-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CUL-5 Antibody (F-6) is a high quality monoclonal CUL-5 antibody (also designated Cullin 5 antibody or CUL5 antibody) suitable for the detection of the CUL-5 protein of mouse, rat and human origin. CUL-5 Antibody (F-6) is available as both the non-conjugated anti-CUL-5 antibody form, as well as multiple conjugated forms of anti-CUL-5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cullin proteins comprise a distinct family of mediators that participate in the selective targeting of proteins for ubiquitin (Ub)-mediated proteolysis. Cul-1, which is the mammalian homolog of Cdc53 from yeast, is an integral component of the E3 ubiquitin ligase complex designated SCF. The SCF (Skp1/Cul-1/F-box protein complex) consists of Skp1 associating with both Cul-1 and an F-box protein, such as Skp2, which determines the substrate specificity of the complex. Cul-1 mediated ubiquitination results in the degradation of cell cycle proteins cyclin D, p21 and cyclin E. Another cullin, CUL-3 facilitates the degradation of cyclin E independent of SCF activity, while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes, which structurally resemble the SCF ligase. Proteolysis also occurs by way of CUL-4 associating with Nedd-8, a ubiquitin-like protein, where it too functions as an active component of a multifunctional E3 complex. CUL-5, or vasopressin-activated, calcium-mobilizing protein (VACM-1), is also included in the cullin family as it shares substantial sequence homology with CUL-1.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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