Date published: 2026-4-24

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Keratin 37 Activators

Keratin 37 activators refer to a specialized category of chemical agents that specifically interact with a type of protein known as Keratin 37, which is one of the numerous members of the keratin family. Keratins, in general, are fibrous structural proteins that are key components of the cytoskeleton of epithelial cells and are critical to the integrity and function of hair, nails, and the outer layer of the skin. Keratin 37 is particularly associated with the microfibrils of hair fibers, contributing to the mechanical strength and resilience of hair. The activators of Keratin 37 are typically small molecules or peptides that can modulate the expression, assembly, or function of this protein. By influencing the behavior of Keratin 37, these activators can affect the properties of hair fibers at a molecular level. They often participate in the complex network of protein-protein interactions that define the architecture and biomechanics of hair.

The action of Keratin 37 activators encompasses a variety of mechanisms, such as enhancing the natural production of Keratin 37 within the cells, stabilizing the protein structure, or facilitating the proper incorporation of Keratin 37 into the intermediate filament network. The composition of these activators can be diverse, ranging from naturally occurring compounds that can be found in the body or in various organisms to synthetic molecules designed to target Keratin 37 with high specificity. The precise interaction of Keratin 37 activators with their target protein depends on the unique structural features of both the activator molecules and the Keratin 37 protein itself.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, essential for skin health, stimulates processes of cell differentiation and growth. This could potentially upregulate Keratin 37 expression by promoting an environment conducive to keratin production.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Cholecalciferol, by promoting cell proliferation and differentiation, could lead to an increase in Keratin 37 expression as these processes are often associated with keratin synthesis.

L-Thyroxine, free acid

51-48-9sc-207813
sc-207813A
100 mg
500 mg
$35.00
$74.00
2
(0)

Thyroxine, a thyroid hormone, plays roles in growth and development. Its action on these processes could potentially stimulate the expression of Keratin 37.

Hydrocortisone

50-23-7sc-300810
5 g
$102.00
6
(1)

Hydrocortisone, a stress hormone, can stimulate various metabolic processes. Its action on these processes could potentially lead to an upregulation of Keratin 37 expression.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$52.00
$298.00
3
(1)

Progesterone, a steroid hormone, stimulates cell proliferation and differentiation. Its action on these processes could potentially induce the expression of Keratin 37.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

β-Estradiol, an estrogen hormone, stimulates cell proliferation and differentiation. Its action on these processes could potentially stimulate the expression of Keratin 37.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin is known to elevate cellular cAMP levels. Increased cAMP can stimulate various signaling pathways, which may lead to an upregulation of Keratin 37 expression.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone is a synthetic corticosteroid known to stimulate various cellular processes including inflammation and cell proliferation, which could potentially induce Keratin 37 expression.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

L-Ascorbic acid (Vitamin C) is an antioxidant that can stimulate cell proliferation and differentiation. Its action on these processes could potentially increase the expression of Keratin 37.