GABAA R α 5 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CL 218872 | 66548-69-4 | sc-203552 sc-203552A | 10 mg 50 mg | $85.00 $319.00 | ||
CL 218872 acts as a selective modulator of the GABA_A receptor, specifically engaging with the alpha-5 subunit. Its unique structural features enable precise binding interactions that stabilize specific receptor conformations, influencing the gating mechanisms of ion channels. The compound demonstrates notable reaction kinetics, characterized by a delayed onset and prolonged effects on synaptic inhibition, thereby modulating neuronal excitability and synaptic plasticity in distinct pathways. | ||||||
TB 21007 | 207306-50-1 | sc-204322 sc-204322A | 10 mg 50 mg | $172.00 $729.00 | ||
TB-21007 is an α5 subunit-selective modulator, influencing the activity of GABAA Rα5 through its unique binding and modulation characteristics. | ||||||
L-838417 | 286456-42-6 | sc-211693 sc-211693A sc-211693B sc-211693C sc-211693D | 5 mg 10 mg 100 mg 500 mg 1 g | $249.00 $430.00 $3000.00 $13500.00 $19500.00 | ||
L-838417 is a selective allosteric modulator of the GABA_A receptor, particularly targeting the alpha-5 subunit. Its unique binding profile enhances receptor affinity, promoting a distinct conformational state that alters ion channel dynamics. This compound exhibits intricate molecular interactions that fine-tune synaptic transmission, leading to specific alterations in neurotransmitter release and receptor desensitization kinetics, ultimately influencing neural circuit behavior. | ||||||