The functional mechanisms of CRBP II activators are primarily centered around the modulation of retinol metabolism and related cellular processes. Compounds like All-trans Retinoic Acid and β-Carotene directly participate in the metabolic pathways of vitamin A, thereby influencing the activity of CRBP II, which is essential in the intracellular transport and metabolism of retinol. All-trans Retinoic Acid, as a biologically active form of vitamin A, enhances CRBP II's role in mediating retinoid signaling, crucial for various physiological processes. β-Carotene, serving as a vitamin A precursor, provides the substrate necessary for retinol synthesis, thereby indirectly enhancing CRBP II's transport and metabolic functions. Citral's role in inhibiting retinal dehydrogenase further exemplifies the indirect modulation of CRBP II activity by altering the levels of retinal, a key intermediate in the metabolism of vitamin A.
Furthermore, the activity of CRBP II is also influenced by the cellular lipid environment, as evidenced by compounds like Lecithin, Oleic Acid, Linoleic Acid, and Palmitic Acid. These fatty acids and phospholipids play significant roles in determining membrane composition and fluidity, which are crucial for the optimal functioning of CRBP II in retinol binding and transport. Cholesterol, another key membrane component, similarly impacts CRBP II by affecting membrane dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Carotene | 7235-40-7 | sc-202485 sc-202485A sc-202485B sc-202485C | 1 g 25 g 50 g 5 kg | $80.00 $351.00 $621.00 $12791.00 | 5 | |
β-Carotene, a precursor of vitamin A, can influence CRBP II by providing a substrate for retinol synthesis, indirectly enhancing its transport and metabolic functions. | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | $135.00 | ||
Lecithin can influence lipid metabolism and membrane composition, potentially affecting CRBP II's activity in transporting retinol within cells. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
Oleic Acid, a fatty acid, can alter membrane fluidity and lipid composition, indirectly affecting CRBP II's role in retinol binding and transport. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $34.00 $64.00 $166.00 $281.00 | 4 | |
Linoleic Acid, another fatty acid, might influence CRBP II by altering cellular lipid environments, which are crucial for the protein's functioning in retinol transport. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $114.00 $286.00 | 2 | |
Palmitic Acid can modify lipid metabolism and membrane dynamics, potentially impacting the functional activity of CRBP II in retinol handling. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $27.00 $2809.00 $129.00 $210.00 $583.00 $88.00 | 11 | |
Cholesterol, a key component of cell membranes, can influence CRBP II's activity by altering membrane properties, affecting retinol transport and metabolism. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B sc-214454C | 10 g 25 g 100 g 1 kg | $43.00 $62.00 $141.00 $430.00 | ||
Vitamin E can modulate oxidative stress and lipid peroxidation, potentially influencing CRBP II's role in retinol metabolism under oxidative conditions. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc, an essential trace element, can modulate enzyme activities in retinol metabolism, potentially impacting CRBP II's functional role in these processes. | ||||||
Copper | 7440-50-8 | sc-211129 | 100 g | $51.00 | ||
Copper can influence various enzymes involved in retinol metabolism, indirectly affecting CRBP II activity in vitamin A handling. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
Selenium, key in antioxidant defense systems, can indirectly influence CRBP II by modulating the cellular redox state, which is crucial for retinol metabolism. | ||||||