Date published: 2026-7-12

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B7-H3 Antibodies

Santa Cruz Biotechnology features a diverse variety of B7-H3 monoclonal antibodies for research focused on immune regulation and tumor biology. B7-H3 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). B7-H3, also known as CD276, is a member of the B7 family of immune checkpoint proteins and plays a critical role in modulating T-cell responses. B7-H3 expression is frequently upregulated in various cancers, making it a significant target for therapeutic intervention and a potential biomarker for tumor progression. Understanding B7-H3 function is essential for developing strategies to enhance anti-tumor immunity. Researchers can investigate B7-H3 expression patterns across different tissue types and cellular conditions. Advanced imaging techniques combined with B7-H3 monoclonal antibodies enable detailed visualization of protein localization and interactions. Comprehensive studies of B7-H3 cellular distribution and regulation contribute to deeper understanding of immune system mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of immune checkpoint regulation and cancer biology.

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B7-H3 Antibodies

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B7-H3 Antibody (F-11)

sc-376769mouse IgG2a κ166-465 (h)WB, IP, IF, IHC(P), ELISAm, r, h
18
(8)

B7-H3 Antibody (C-1)

sc-398323mouse IgG2b κ82-107 (h)WB, IP, IF, ELISAm, r, h

new

(2)

B7-H3 Antibody (D-8)

sc-398444mouse IgG2b κ83-108 (h)WB, IP, IF, ELISAm, r, h
1
(1)

B7-H3 Antibody (G-8)

sc-376535mouse IgG1 κ166-465 (h)WB, IP, IF, ELISAm, r, h
2
(1)

B7-H3 Antibody (G-12)

sc-398403mouse IgG1 κ82-107 (h)WB, IP, IF, ELISAm, r, h
1
(2)

B7-H3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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B7-H3 siRNA (h)

sc-45444hGene SilencingN/A
3
(0)

B7-H3 shRNA Plasmid (h)

sc-45444-SHhGene SilencingPuromycin
3
(0)

B7-H3 shRNA (h) Lentiviral Particles

sc-45444-VhGene SilencingPuromycin
3
(0)

B7-H3 siRNA (m)

sc-45445mGene SilencingN/A0
(0)

B7-H3 shRNA Plasmid (m)

sc-45445-SHmGene SilencingPuromycin0
(0)

B7-H3 shRNA (m) Lentiviral Particles

sc-45445-VmGene SilencingPuromycin0
(0)

B7-H3 CRISPR Knockout (KO) and HDR Plasmids

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B7-H3 CRISPR/Cas9 KO Plasmid (h)

sc-402032Gene Knockouth0
(0)

B7-H3 HDR Plasmid (h)

sc-402032-HDRHomology Directed Repairh0
(0)

B7-H3 CRISPR/Cas9 KO Plasmid (m)

sc-430440Gene Knockoutm0
(0)

B7-H3 HDR Plasmid (m)

sc-430440-HDRHomology Directed Repairm0
(0)

B7-H3 CRISPR Double Nickase Plasmids

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B7-H3 Double Nickase Plasmid (h)

sc-402032-NICGene Knockouth0
(0)

B7-H3 Double Nickase Plasmid (h2)

sc-402032-NIC-2Gene Knockouth0
(0)

B7-H3 Double Nickase Plasmid (m)

sc-430440-NICGene Knockoutm0
(0)

B7-H3 CRISPR Activation Plasmids and Lentiviral Particles

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B7-H3 CRISPR Activation Plasmid (h)

sc-402032-ACTGene Activationh0
(0)