Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF313 (Zinc finger protein 313), also known as RNF114 (RING finger protein 114) or ZNF228, is a 228 amino acid protein that contains one RING-type zinc finger (a domain that can bind two zinc atoms and is involved in the ubiquitination pathway) and is expressed abundantly in mature testis. Existing as two isoforms due to alternative splicing events, ZNF313 is thought to play a role in spermatogenesis and male fertility. In addition, the gene encoding ZNF313 may be associated with an increased susceptibility to psoriasis, an immune-mediated skin disease characterized by red, scaley patches on the epidermis.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ZNF313 (SM-3) | sc-101116 | 100 µg/ml | $333.00 |