Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFAND2B (AN1-type zinc finger protein 2B) is a 257 amino acid protein containing two AN1-type zinc fingers and two UIM (ubiquitin-interacting motif) repeats. Conserved in animals and plants, the AN1-type zinc finger domain is often found in proteins that contain a ubiquitin-like domain, which suggests a role in the ubiquitination pathway. There are two isoforms of ZFAND2B that are produced as a result of alternative splicing events.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ZFAND2B (F-2) | sc-398044 | 200 µg/ml | $316.00 | |||
ZFAND2B (F-2) peptide neutralisant | sc-398044 P | 100 µg/0.5 ml | $68.00 |