Date published: 2025-9-9

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Anticorps VRK1 (1F6): sc-101554

4.0(1)
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Fiches techniques
  • L'Anticorps VRK1 (1F6) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 200 µg/ml
  • dirigé contre la VRK1 recombinante d'origine human
  • recommandé pour la détection de VRK1 d'origine mouse, rat et human par WB et IP
  • 1 BP-HRP">m-IgG1 BP-HRP est le réactif de détection secondaire préféré pour l'anticorps VRK1 (1F6) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps VRK1 (1F6)(voir les informations relatives à la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Human vaccina-related kinases 1 and 2 (VRK1,2) are NLS-containing, serine/threonine poxvirus-related kinases that are similar to casein kinase-1 family members. These VRK kinases phosphorylate transcription factors related to stress responses, such as p53. As an upstream regulator of p53, VRK-1 is capable of phosphorylating phosvitin, casein, histone 2b and myelin basic protein. VRK1 co-localizes with ATF2 in the nucleus and can form a stable complex. VRK1 phosphorylates ATF2 mainly on Thr 73, stabilizing the ATF2 protein and increasing its intracellular level. VRK1 phosphorylates human p53 in Thr18 and disrupts p53-Mdm2 interaction in vitro. VRK1 phosphorylates c-Jun in Ser 63 and Ser 73 in vitro (the same residues targeted by the N-terminal kinase of c-Jun (JNK)), and activates c-Jun dependent transcription.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps VRK1 (1F6)

sc-101554
200 µg/ml
$316.00

VRK1 (1F6): m-IgG1 BP-HRP Kit

sc-542633
200 µg Ab; 20 µg BP
$354.00

May I know which exon the antibody recognising in human cells? Thanks! 

Posée par: Mandy
Thank you for your question. Please contact technical service by emailing scbt@scbt.com
Répondue par: BlakeJ
Date de publication: 2024-03-28

Are there any issues with using sc-101554: VRK1 (1F6) mouse monoclonal primary antibody on mouse samples?

Posée par: jenniferc
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-101554 conjugates.
Répondue par: Technical Support
Date de publication: 2017-03-07
  • y_2025, m_8, d_29, h_8CST
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Rated 4 de 5 de par WB publishable data with human WS1WB publishable data with human WS1 - SCBT Publication Review
Date de publication: 2014-12-11
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Anticorps VRK1 (1F6) est évalué 4.0 de 5 de 1.
  • y_2025, m_8, d_29, h_8
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  • cp_1, bvpage1
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  • loc_fr_FR, sid_101554, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
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