Anticorps TLK2 (Y-17): sc-100346
- L'Anticorps TLK2 (Y-17) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la TLK2 recombinante d'origine human
- recommandé pour la détection de TLK2 d'origine human par WB, IP, IF, IHC(P) et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire TLK2 (Y-17). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The Tousled-like kinases (TLK1 and TLK2, also designated PKU-β and PKU-α, respectively) are the human homologs of the Tousled gene from Arabidopsis thaliana, which encodes a Serine/Threonine kinase that is necessary for proper organ morphogenesis. Both TLKs contain a nuclear localization signal and a predicted coiled-coil region in the N-terminal domain. TLK is ubiquitously expressed, and is prevalent in mouse testis, especially in pachytene spermatocytes and round spermatids. It displays a propensity to dimerize through an interaction between its coiled-coil structure and is able to autophosphorylate, as well as phosphorylate exogenous substrates. TLK1 and TLK2 are regulated by the cell cycle, showing maximum activity during S phase. Subsequently, they are thought to regulate the development of multicellular organisms, including playing a key role in spermatogenesis, through a series of phosphorylations.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TLK2 (Y-17) | sc-100346 | 100 µg/ml | $333.00 |